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Biomedical subjects

Francis J Lannigan

Publications and source records attributed to Francis J Lannigan.

7 recordsLinked to original sources
PubMed2006

Adenotonsillectomy for obstructive sleep apnea in obese children: effects on respiratory parameters and clinical outcome.

OBJECTIVE: To assess the efficacy of adenotonsillar surgery on respiratory sleep parameters and avoiding continuous positive airway pressure (CPAP) treatment in morbidly obese children with obstructive sleep apnea syndrome (OSAS). DESIGN: Retrospective. SETTING: Tertiary referral institution. PATIENTS: Children aged 2 to 18 years, with a body mass index (BMI) at or higher than the 95th percentile (adjusted for age and sex), undergoing adenotonsillar surgery for OSAS. INTERVENTIONS: Adenotonsillectomy. MAIN OUTCOME MEASURES: Preoperative and postoperative respiratory disturbance index, oxygen saturation nadir, overall severity of OSAS (mild, moderate, or severe) and candidacy for CPAP treatment were assessed and compared. Variables such as age, severity of disease, adenotonsillar size, and BMI z scores were compared between responders and nonresponders to surgical treatment. RESULTS: A total of 19 patients with full preoperative and postoperative data for evaluation were identified. The median (SD) age was 78 months (53.3 months). The median (SD) BMI z score was 2.84 (0.94). Eighteen patients (95%) had OSAS preoperatively to warrant CPAP treatment. Surgery reduced the overall median (SD) respiratory disturbance index from 20.7 (24.5) to 7.3 (14.9) (P<.001) and improved the median (SD) oxygen saturation nadir from 77.5% (16.3%) to 88.5 (13.1%) (P<.01). A total of 7 patients (37%) were cured by surgery. Ten patients (53%) had postoperative disease of sufficient severity to require CPAP. Surgery obviated the need for further treatment in only 8 (44%) of the 18 patients with preoperative disease warranting CPAP. No differences were identified between responders and nonresponders to surgical treatment. CONCLUSIONS: Adenotonsillar surgery improves sleep respiratory parameters in morbidly obese children with OSAS. Most patients have residual OSAS requiring further treatment.

Adenoidectomy↗
PubMed2006

Decreasing rates of middle ear surgery in Western Australian children.

OBJECTIVE: To investigate temporal, social, demographic, and health care utilization factors associated with myringotomy with ventilation tube insertion (MVTI) in Western Australian (WA) children. DESIGN: Observational retrospective population-based cohort study using hospital administrative data. SETTING: All WA hospitals. PARTICIPANTS: A total of 53 673 children younger than 15 years who underwent surgery for MVTI in the period 1981-2004. MAIN OUTCOME MEASURES: Age-specific incidence rates and incidence rate ratios. RESULTS: The rate of MVTI in children younger than 15 years peaked in 1997 at 6.7 per 1000 person-years and decreased to 5.6 per 1000 person-years by 2004. Based on 2004 rates, 8.4% of WA children will undergo at least 1 MVTI procedure before reaching age 15 years. The rate of MVTI was 37% lower in Indigenous children, and the procedures were performed at an older age compared with non-Indigenous children. Higher rates of MVTI were associated with areas of higher economic resources, lower education and occupation status, and living in metropolitan areas. CONCLUSIONS: The rate of MVTI in WA is showing evidence of a decline, even among children younger than 5 years. There remains an issue regarding equity of access to care for Indigenous children. Increasing parental economic resources may be associated with higher rates of MVTI independent of educational status.

Adolescent↗
PubMed2005

Obstructive sleep apnea, morbid obesity, and adenotonsillar surgery: a review of the literature.

Obstructive sleep apnea syndrome is a common occurrence in the obese pediatric population. As this subgroup is rapidly expanding, these children will be increasingly encountered by the otolaryngologist in practice. The literature regarding the etiology, pathogenesis, diagnosis and surgical treatment of obstructive sleep apnea in morbidly obese children is reviewed and pertinent data presented.

Adenoidectomy↗
PubMed2005

Congenital cervical teratomas: diagnostic, management and postoperative variability.

OBJECTIVE: To review the diagnosis, management and outcomes of congenital cervical teratomas presenting to a tertiary referral centre. METHODS: Retrospective chart review of three cases presenting within an 18-month period. RESULTS: Of the three patients in this series, one was diagnosed antenatally. The remaining cases were diagnosed at birth. The antenatally diagnosed patient underwent an EXIT procedure whereby the airway was secured by tracheostomy. This patient subsequently died 30 min after separation from the materno-foetal circulation. Neither of the other two cases had any neonatal respiratory distress, despite having large tumours. Both patients had neonatal surgical excision of the teratomas performed. Both patients had postoperative respiratory distress, requiring intervention. Both patients made a full recovery. No recurrence has been reported. CONCLUSION: The antenatal diagnosis of large congenital cervical teratomas allows for planned intervention by experienced personnel. A successful outcome may not be obtained. All patients that undergo surgical excision of these tumours must be closely observed for post-operative respiratory distress, even in the absence of pre-operative symptoms.

Adult↗