Franco Lepore — Page 2

PubMed2002

Phase disparity in area 19 of the cat.

Binocular cells in area 19 are tuned to positional disparities. In effect, up to one-third of the cells respond preferentially to small incongruities between the optimal bar stimuli presented within the receptive fields of each eye. The aim of the present study was to determine whether cells in area 19 are also sensitive to phase disparities. Both types of disparities have been proposed as mechanisms through which stereoperception is achieved. Results indicate that phase disparities produced coherent interactions in 38% of the binocular cells, resulting in facilitation or summation. The remaining cells were phase insensitive. The overall results suggest that cells in area 19 code phase disparities in a proportion comparable to stimulus disparities, confirming that this area is implicated in binocular integration, albeit in a relatively smaller proportion than some of the other visual areas.

Animals↗

PubMed2002

Sound localization in callosal agenesis and early callosotomy subjects: brain reorganization and/or compensatory strategies.

In order to evaluate the callosal involvement in sound localization, the present study examined the response accuracy of acallosal and early callosotomized subjects to monaural and binaural auditory targets presented in three-dimensional space. In these subjects, bilateral localization cues, such as interaural time and level differences, are integrated at the cortical and subcortical levels without the additional support of the callosal commissure. Because acallosal and early-callosotomized subjects have developed with this reduced source of binaural activation of cortical cells, they might have perfected their ability to use monaural sound localization cues. This hypothesis was tested by assessing localization performance under both binaural and monaural listening conditions. Five subjects with callosal agenesis, one callosotomized subject operated early in life and 19 control subjects were asked to localize broad-band noise bursts (BBNBs) of fixed intensity in the horizontal plane in an anechoic chamber. BBNBs were delivered through randomly selected loudspeakers. Two conditions were tested: (i) localization of a stationary sound source; and (ii) localization of a moving sound source. Listeners had to report the apparent stimulus location by pointing to its perceived position on a graduated perimeter. The results indicated that the acallosal subjects were less accurate than controls, but only in the binaural moving sound condition. More interestingly, in the monaural testing conditions, some of the acallosal subjects and the early-callosotomized subject performed significantly better than control subjects. This suggests that, because of the absence of the corpus callosum, these subjects compensate for their reduced access to cortically determined binaural cues by making more efficient use of monaural cues.

Acoustic Stimulation↗