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Frank Bloos

Publications and source records attributed to Frank Bloos.

5 recordsLinked to original sources
PubMed2006

Ultrasound-guided central venous cannulation: is there a difference between Doppler and B-mode ultrasound?

STUDY OBJECTIVE: To compare the success of Doppler and B-mode ultrasound-guided internal jugular vein (IJV) catheterization with respect to body mass index (BMI). STUDY DESIGN: Prospective, randomized study. SETTING: Section for cardiovascular anesthesia of a university hospital. PATIENTS: 338 consenting patients were analyzed. INTERVENTIONS: Subjects receiving central venous catheters for scheduled cardiac surgery were divided into two groups. After induction of general anesthesia, the right or left IJV was assessed for midcervical cannulation approach. In the Doppler group (n = 189), a SonoGuide2 with a 5.0-MHz probe was used. In the B-mode group (n = 149), the SiteRite II ultrasound system with a 7.5-MHz transducer was used. MEASUREMENTS AND MAIN RESULTS: There was a significant difference in the success rate of first needle pass between the two groups: Doppler group, 91% (172/189); B-mode group, 96.6% (144/149) (P = 0.045). A BMI of 30 and greater was associated with a significantly lower first needle pass success rate in the Doppler group (Doppler group, 77.1% [27/35]; B-mode group, 97.4% [38/39]; P = 0.011). The success rates in patients with a BMI below 30 for both methods were not different (Doppler group, 94.2% [145/154]; B-mode group, 96.4% [106/110]; P = 0.567). Arterial punctures occurred three times under Doppler guidance and twice under B-mode guidance. CONCLUSION: Cannulation of the IJV can be ensured and first needle pass success rate maximized by both ultrasound techniques. In patients with a BMI greater than 30, B-mode technique is superior to Doppler ultrasound.

Adolescent↗
PubMed2005

Venous oximetry.

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Cardiac Output↗
PubMed2005

Neutrophil stimulation with granulocyte colony-stimulating factor worsens ventilator-induced lung injury and mortality in rats.

BACKGROUND: Based on the association between the neutrophil and ventilator-induced lung injury, the authors hypothesized that neutrophil inhibition with fucoidin would be beneficial and stimulation with granulocyte colony-stimulating factor (G-CSF) would be harmful in a rat model of lethal ventilator-induced lung injury. METHODS: Animals (n = 111) were randomly assigned to be pretreated with fucoidin, G-CSF, or placebo (control) before 4 h of low-tidal-volume (10 ml/kg) or high-tidal-volume (40 ml/kg) mechanical ventilation. RESULTS: All low-volume animals survived. With high volumes, compared with controls, fucoidin did not improve survival (3 of 20 control animals and 5 of 20 fucoidin animals died; P = 0.51) but G-CSF significantly worsened it (18 of 22 animals died; P < 0.001). Circulating neutrophils were increased early with G-CSF and late with fucoidin with low and high tidal volumes (P < 0.05 for each treatment and tidal volume). Fucoidin decreased lung neutrophils, but these were only significant with high tidal volumes, whereas G-CSF increased lung neutrophils but only significantly with low tidal volumes (P < or = 0.01 for each). Fucoidin did not alter any cardiopulmonary measure significantly. Compared with control, G-CSF increased airway pressures with high tidal volumes and worsened lung edema and arterial oxygen with both tidal volumes (P < 0.05 for each). CONCLUSIONS: In this model, neutrophil stimulation by G-CSF increased lung dysfunction and with high tidal volumes worsened survival rates. Extrapolated clinically, neutrophil stimulation either by agents such as G-CSF or conditions such as sepsis may aggravate ventilator-induced lung injury.

Animals↗
PubMed2005

The value of venous oximetry.

PURPOSE OF REVIEW: Maintenance of adequate tissue oxygenation is an important task in intensive care units. In this context, venous oximetry by obtaining mixed venous oxygen saturation or central venous oxygen saturation has been discussed as useful monitoring parameters. This review discusses the physiology and clinical application of these parameters. RECENT FINDINGS: No study has so far demonstrated that venous oxygen saturation monitoring can reduce mortality in critically ill patients although length of stay has been decreased in cardiac surgery patients. Furthermore, pulmonary artery catheter usage does not affect outcome in critically ill patients. In contrast, early goal directed therapy for patients with severe sepsis or septic shock, which includes treatment goals for mean arterial pressure, central venous pressure, and central venous oxygen saturation, was able to increase survival in these patients. There is also evidence that central venous oxygen saturation measurement is beneficial in other types of shock. SUMMARY: Early goal directed therapy should be implemented in the initial resuscitation of septic patients. Measurement of central venous oxygen saturation can easily be applied in intensive care unit patients and offers a useful indirect indicator for the adequacy of tissue oxygenation.

Blood Gas Analysis↗