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Biomedical subjects

Fred J Spielman

Publications and source records attributed to Fred J Spielman.

6 recordsLinked to original sources
PubMed2004

The smell of sleep.

Explore the source record for details and available documents.

Portraits as Topic↗
PubMed2002

Complete separation of the tube from the mask during removal of a disposable laryngeal mask airway.

PURPOSE: To describe a complication of the disposable laryngeal mask airway (LMA). CLINICAL FEATURES: A 23-yr-old woman underwent a wide local excision of a chest wall melanoma and sentinel node biopsy under general anesthesia. During use of a single-use LMA-Unique(TM), the airway tube became completely separated from the distal mask (backplate). No sequelae resulted from failure of the airway apparatus. The LMA was examined by LMA North America, and the company stated "no definitive explanation can be made to explain the cause for separation of the airway from the backplate." CONCLUSION: Although the use of the LMA is associated with rare and minimal complications, each airway should be carefully inspected before its use for loss of integrity resulting from sterilization or for defects in manufacturing.

Adult↗
PubMed1988

Alterations in cerebrospinal fluid concentrations of somatostatin-like immunoreactivity in chronic pain patients.

Concentrations of somatostatin-like immunoreactivity in cerebrospinal fluid were significantly reduced in chronic pain patients compared to control patients without chronic pain. This difference was not influenced by demographic or clinical characteristics. Somatostatin has been shown to be a neurotransmitter in animal nociception; pharmacologic doses of this substance have moderated human pain. Our findings provide evidence that somatostatin may be involved in the pathogenesis of the chronic pain state.

Adult↗