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Fuat Gundogdu

Publications and source records attributed to Fuat Gundogdu.

9 recordsLinked to original sources
PubMed2006

Effect of beta-blocker therapy on left atrial function in patients with heart failure: comparison of metoprolol succinate with carvedilol.

OBJECTIVE: We aimed to compare the effects of carvedilol and metoprolol succinate on left atrial (LA) function in patients with chronic heart failure. METHODS: Thirty three patients (6 females, 27 males) who had not received beta blocker treatment previously and whose left ventricular ejection fraction was below 40% were included in this study. LA volumes were measured echocardiographically just before the time of mitral valve opening (V (max)), onset of atrial systole (p-wave at the electrocardiography = V (p)) and mitral valve closure (V (min)) according to the biplane area length method at baseline and in the 3rd month after the administration of beta blockers. NT-proBNP level was measured at the beginning and in the third month of beta blocker treatment. The first group was given carvedilol 6.25 mg/day, the second group was given 12.5 mg/day metoprolol succinate and it was increased to the tolerable maximal dose. RESULTS: LA diameter and LA V (max), V (p), V (min) decreased significantly both in carvedilol group and metoprolol group after beta blocker theraphy (P < 0.01, : P < 0.01, : P < 0.05, : P < 0.05: for metoprolol, P < 0.001, P < 0.01, P < 0.01, P < 0.01 for carvedilol). But it was increased in conduit volume (P < 0.05 for two groups). LA-passive emptying fraction, LA-active emptying fraction and reservoir fraction were no significant differences both in carvedilol group and metoprolol group after beta blocker theraphy. NT-proBNP levels were found to decrease significantly in both groups after beta blocker treatment (P < 0.001).: CONCLUSION: Our findings indicate that beta blocker treatment leads to a decrease in LA diameters and volumes, and metoprolol succinate and carvedilol had similar effects on this decrease.

Adrenergic beta-Antagonists↗
PubMed2006

Left ventricular noncompaction and mid-caviter narrowing associated with Ebstein's anomaly: three-dimensional transthoracic echocardiographic image.

An 50 year-old asymptomatic female was admitted to preoperative cardiovascular evaluation for noncardiac surgery. Two-dimensional transthoracic echocardiography demonstrated that left ventricular dimensions and ejection fraction were normal. The mitral valve was normal both in morphology and function. The attached margin of septal and anterior leaflet of the tricuspid valve was apically displaced. But right ventricle and right atrium dimensions were normal, and Doppler interrogation showed a slight tricuspid regurgitation. Two and three-dimensional transthoracic echocardiography showed prominent numerous trabeculations in the left ventricular apex. Colour flow Doppler studies confirmed the presence of blood flow within the trabeculations. Multi-plane three-dimensional transthoracic echocardiography showed a muscular band leading to left ventricular mid-caviter narrowing. Pulse wave Doppler echocardiography demonstrated that no intraventricular gradient existed. Ventricular noncompaction associated with Ebstein's malformation has been reported. But left ventricular noncompaction and mid-caviter narrowing associated with Ebstein's anomaly have not been reported so far.

Ebstein Anomaly↗
PubMed2006

Congenitally corrected transposition of the great arteries: MDCT angiography findings and interpretation of complex coronary anatomy.

A 56-year-old male patient was admitted to our hospital because of dyspne and chest pain. A chest radiograph showed mild cardiomegaly. Echocardiography revealed unusual chamber in the heart. The chamber beneath the left atrium was morphologically right ventricle. To evaluate the precise complex anatomy of this abnormality, multidetector computed tomography (MDCT) angiography was performed. MDCT clearly revealed complex intracardiac and vascular anatomy, including typical imaging findings of a patient with congenitally corrected transposition of the great arteries (CCTGA). We described both imaging findings of MDCT angiography and interpretation of complex vascular anatomy in a patient with CCTGA.

Coronary Angiography↗
PubMed2006

Coronary artery fistula in a patient with coronary artery disease: evaluation by coronary angiography and multidetector computed tomography.

A 54-year-old man with acute myocardial infarction was successfully treated with coronary artery stenting. Coronary angiography is the preferred diagnostic method for imaging the coronary arteries, but coronary artery fistulas origin and course may not be apparent. New tomographic cardiovascular imaging tests such as, multidetector computed tomography (MDCT) can be used to precise delineation of coronary fistulas.

Arterio-Arterial Fistula↗
PubMed2006

Asymptomatic cardiac lipoma originating from the interventricular septum diagnosed by multi-slice computed tomography.

A 45 year-old asymptomatic man was admitted to preoperative cardiovascular evaluation for noncardiac surgery. Physical examination and ECG were normal. Transthoracic echocardiography showed a 17 x 35 mm suspicious hyperechoic mass in the interventricular septum. Multi-slice computed tomography (MSCT) was used. Volume rendered image and an axial maximal intensity projection image demonstrated a mass with a density consistent with fat tissue ( - 78 HU). The MSCT findings were diagnostic of a benign lipoma. Thus, this mass was noninvasively diagnosed as cardiac lipoma. Neither life-threatening arrhythmia on Holter monitoring nor myocardial ischemia on exercise scintigraphy was observed.Transthoracic echocardiography is usually the initial diagnostic test in patients with a suspected cardiac mass. However, its sensitivity for differentiating tissue characteristics is limited. MSCT allow for detailed delineation of intra and pericardiac masses. In conclusion, we demonstrated the value of cardiac MSCT to diagnose an interventricular lipoma.

Echocardiography↗
PubMed2006

The evaluation of myocardial damage in 83 young adults with carbon monoxide poisoning in the East Anatolia region in Turkey.

Carbon monoxide (CO) poisoning is the leading cause of death from intoxication. In CO poisoning, it is important to know if there are any symptoms regarding myocardial damage, which are usually unobserved as a result of hypoxia. This study was planned to assess myocardial damage in young healthy patients with CO poisoning. Eighty-three young healthy cases who had been exposed to CO were included in this study. The demographic and clinical characteristics, the origin of CO gas and smoking habits of the patients were recorded. The evaluation of ECG, peripheral ABG, complete blood count and serial cardiac biomarkers (creatine kinase, creatine kinase-myocardial band and troponin I) measurements were performed in all cases. Additionally, echocardiogram (ECHO) and myocardial perfusion single-photon emission computed tomography (SPECT) were performed at the appropriate times in all cases. The mean age of the patients was 27.3 +/- 10.9 years. The main complaint of the patients was loss of consciousness with a 62.7% rate. The average carboxyhaemoglobin level of the patients was 34.4 +/- 15.9%. Sinus tachycardia was present in 26.5% of patients. Diagnostic ischaemic ECG changes were present in 14.4% of patients. In myocardial SPECT, myocardial ischaemic damage was observed in 9 cases, in 6 of whom ECHO findings were also confirmed. Myocardial damage due to CO poisoning should not be ignored. If patients are at risk in terms of myocardial damage, further studies, such as ECHO and scintigraphy are needed to determine myocardial damage resulting from CO poisoning. However, in the young adults of the risk group, if the baseline ECG and serial cardiac biomarkers are normal, further studies such as ECHO and scintigraphy, considering the length of exposure and the severity of poisoning, may not be necessary for the evaluation of myocardial damage due to CO poisoning.

Adolescent↗
PubMed2005

The use of anatomic M-mode echocardiography to determine the left atrial appendage functions in patients with sinus rhythm.

Left atrial appendage (LAA) contractile dysfunction is associated with thrombus formation and systemic embolism. LAA function is determined by its flow velocities and fractional area change. This study was performed in order to determine the LAA functions with the anatomic M-mode echocardiography (AMME). Our study comprised 74 patients who had sinus rhythm and underwent transesophageal echocardiography (TEE) for various reasons. LAA fractional change (LAAFAC) was measured by manual planimetry in a transverse basal short-axis approach and LAA emptying and filling velocities also were measured. The AMME values were determined by an M-mode cross section from a cursor placed beneath the orifice of the LAA in transverse basal short-axis imaging. From these values LAA fractional shortening (LAAFS) and ejection fraction (LAAEF) were calculated. LAAEF was calculated by the Teicholz method. The comparisons were conducted, and no correlations between the LAA late filling and the anatomic M-mode values were found (for LAAFS r = 0.18; P > 0.05 and for LAAEF r = 0.19; P > 0.05). There were significant but poor correlations among the LAA late emptying with the anatomic M-mode measurements (for LAAFS r = 0.26; P < 0.05 and for LAAEF r = 0.30; P < 0.01), whereas, there were significant and good correlations between the LAAFAC and the anatomic M-mode values (for LAAFS r = 0.75; P < 0.01 and for LAAEF r = 0.78; P < 0.01). There were significant differences between the valvular heart disease group and the normal group, and between the valvular heart disease group and the ASD group (for LAAFAC P < 0.01, for LAAEF P < 0.01, for LAAFS P < 0.01). There was no difference between the normal group and the ASD group. Our study showed that the LAAEF and LAAFS in patients with sinus rhythm obtained via anatomical M-mode echocardiography is a new method, which can be used instead of left atrial appendage area change.

Adult↗
PubMed2005

Left atrial mechanical functions in pre-eclampsia.

AIM: To assess the effect of short-term pressure overload on left atrial (LA) mechanical function in pre-eclampsia. METHODS: Twenty women with pre-eclampsia and 17 age-matched healthy pregnant women were included. LA volumes were measured echocardiographically at the time of mitral valve opening (Vmax), onset of atrial systole (p-wave at the electrocardiography = Vp) and mitral valve closure (Vmin) according to the biplane area-length method. RESULTS: The mean age, gestational age, weight and body surface area were similar in pre-eclampsia and controls. The ventricular septal and posterior wall thickness were greater in pre-eclampsia (P < 0.001). There were no significant differences in LA diameter, Vmax, Vmin, Vp, LA-passive emptying volume, LA-passive emptying fraction, LA-active emptying volume, LA-active emptying fraction, conduit volume, LA-total emptying volume and LA-total emptying fraction between the groups. CONCLUSION: Left atrial mechanical function didn't change in pre-eclampsia. We conclude that short-lasting pressure overload is not capable of inducing changes in LA function.

Adult↗