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Biomedical subjects

G A Binda

Publications and source records attributed to G A Binda.

15 recordsLinked to original sources
PubMed2004

A novel approach for perirectal tumours: the perianal intersphincteric excision.

INTRODUCTION: Several procedures have been described for the excision of perirectal tumours. Among them are the Kraske and York Mason operations, and the transanal approach, which may cause anal incontinence and rectal bleeding. A novel technique, i.e. the perianal intersphincteric excision (PIE), is reported here with the aim of minimising such postoperative complications, as it avoids both stretching the sphincters and endorectal wounding. CASE REPORT: The procedure has been carried out successfully in two patients: a woman with a low-grade rectal leiomyosarcoma and a man with a perirectal schwannoma. No postoperative complications were observed, and no recurrence was detected after 36 and 8 months respectively. CONCLUSION: In conclusion, PIE seems to be a safe and effective procedure for the management of perirectal masses.

Adult↗
PubMed2004

Indications for colorectal resection for adenoma before and after polypectomy.

Adenomas presenting in colon and rectum require different strategies. Those in the rectum are accessible to local endoanal excision while those in the colon can be removed by endoscopic polypectomy. Essentially the decision in both cases centres around the risk of malignancy. Does the tumour itself contain a focus of malignancy? Where invasion has been demonstrated in the tumour, are the regional lymph nodes involved? Rectal adenomas can be assessed by clinical examination, rectal ultrasound and magnetic resonance imaging. Colonic adenomas on the other hand, are assessed by endoscopic appearances amplified by chromo- and zoom-endoscopy techniques and by endoscopic endosonography. In both locations the decision for surgical resection may be necessary in two clinical circumstances: the preoperative assessment of invasion and following the histopathology report where invasion has been demonstrated. With any adenoma with malignant change, a surgical opinion should be obtained. The decision for surgery depends on the risk of failure of the local excision balanced by the risk of morbidity and mortality following major surgery. Patients' wishes in the light of discussion of clinical and pathological prognostic factors are crucial in making the decision. Surgery is more frequently applied for early colonic than rectal cancers. This is due to two main factors: resective colonic surgery has less complications and mortality than anterior resection and transanal local excision may be more radical than endoscopic colonic polypectomy because it excises the full-thickness rectal wall.

Adenoma↗
PubMed1987

Effect of timepidium bromide on the motor activity of the sphincter of Oddi: manometric evaluation of intracholedochal pressure.

The intracholedochal pressure changes induced by timepidium bromide were studied in 12 patients who had undergone surgery because of gall bladder stones and were receiving transient external bile drainage by the Kehr method. Cholangiomanometric examination, carried out under basal conditions and after an intravenous dose of 15 mg timepidium bromide, revealed a statistically significant decrease in mean intracholedochal pressure in all 12 patients. It is concluded that timepidium bromide is likely to exert a direct action on the sphincter of Oddi, decreasing its basal tone and thus causing a decrease in intracholedochal pressure.

Aged↗
PubMed1987

[Intramural diverticulosis of the gallbladder].

The authors report on 9 cases of acalculous adenomyomatosis of the gallbladder, selected to Arianoff's classification. The clinical, anatomopathological and radiological data are considered: there isn't difference concerning the clinical symptoms between adenomyomatosis and cholelithiasis; only radiological study may clarify the nature and character of these lesions. The authors conclude stressing the importance of surgical therapy because the medical therapy is only symptomatic and does not modify the natural evolution of the disease and its complications.

Adult↗
PubMed1980

[The role of endoscopy and histology in the diagnosis of esophagitis].

An assessment is made of the meaningfulness of endoscopy and histology in the diagnosis of oesophagitis via an examination of 240 endoscopies. An endoscopic diagnosis of oesophagitis was given in 69 cases. Biopsy was performed in only 44 cases. This confirmed the endoscopic diagnosis on all but one occasion. There were 1 histological and 10 endoscopic false negatives. It is suggested, therefore, that perendoscopic biopsy should always be performed to reduce false negatives in cases where oesophagitis or gastro-oesophageal reflux is suspected, or when hiatal hernia (even if asymptomatic) is present.

Biopsy↗
PubMed1980

[Biofeedback and esophageal manometry. Preliminary note].

The biofeed-back technique is based on the concept of the voluntary control of visceral functions and derives from the clinical application of the theory of operative conditioning. After a brief mention of general concepts and the various application fields of biofeed-back, a personal proposal for the use of this technique in the treatment of oesophageal dysfunctions of psychosomatic origin with the aid of oesophageal manometry is put foward.

Animals↗
PubMed1980

[Manometric study of the upper esophageal sphincter in normal subjects and in patients with achalasia of the cardia].

The authors explored the motor behavior of the upper esophageal sphincter in normal subjects and in patients with achalasia of the cardia, in a manometric investigation involving the measurement of intraluminal pressure both with axial and with radial catheters. The former were used to assess motor coordination between the various segments of the esophagus; the latter for recording basal pressure along various diameters. The data concerning pressure at rest, relaxation time, and motor coordination relative to adjacent segments, were then compared with the corresponding data obtained in a group of patients treated surgically by Heller cardiomyotomy and Dor, antireflux esophagoplasty, and then with those obtained in a group of normal subjects. Statistical processing of data by the T test of STUDENT failed to reveal any significant differences between the three groups being compared. This is taken to mean complete motor independence of the upper esophageal sphincter in achalasia in relation to the remaining segments of the esophagus, whereas these segments are themselves subject to considerable variations of pressure and motility.

Esophageal Achalasia↗
PubMedDate not supplied

Emergency surgery of complicated colonic diverticulitis.

Colon diverticular disease is an increasingly frequent disorder especially in Western populations characterized by high living standards. In 30-40% of subjects over 60 years of age barium enema detects the presence of diverticula in the sigma. 10-20% of patients affected by colon diverticular disease develop complications such as inflammation or haemorrhage and 20-30% of these patients undergo surgery (60% of patients aged less than 40). Emergency surgery is performed in 50% of cases and it is currently burdened by high mortality rates. We decided to review our cases history to clarify the indication for emergency surgery, the appropriateness to resect the diseased bowel tract and to perform colic anastomosis at the time of emergency resection.

Adult↗