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Biomedical subjects

G A Bothmann

Publications and source records attributed to G A Bothmann.

6 recordsLinked to original sources
PubMed1984

[Plate thermography in the assessment of changes in the female breast. 1. The value of malignancy criteria using Tricoire's technic].

In a retrospective study on 19,641 patients of which 2702 were clarified by morphology criteria of malignancy by Tricoire were examined. Nearly all criteria were relevant. Only the "mild circumscript heatness " and "one atypical vessel" have failed as criteria of malignancy. The vascular pattern D + E ( Bourjat ) is shown as an additive sign of malignancy. The correct classification in typical and atypical vascular patterns depends from a decisive dynamic test.

Breast↗
PubMed1981

[Measurement of skin temperature in breast cancer--a new possibility of early diagnosis].

The local skin temperature was measured by infrared thermometry in 100 women suffering from malign neoplasms of the breast. After thermal stimulation the reaction of the skin temperature was determined in a repeated measurement. The results were compared with standard temperature values obtained in 100 healthy women. Statistical evaluation of the data using discriminant analysis resulted in a score, which allowed to classify 90% of the women with mamma carcinomas and 92% of the controls correctly. The possible application of this passive diagnostic method to the early detection of malign tumors in the breast is discussed.

Adult↗
PubMed1976

[Correlations between metric, cyto and histomorphological factors and thermographic findings in breast neoplasms].

Correlations between metric, cyto- and histomorphological characteristics and thermographical results of 119 carcinomas of the breast have been studied by statistical methods. For the purpose of semi-quantitative evaluation the chi2 of 14 characteristics were calculated from foursquare tables and summarized in a correlation matrix. The study revealed a significant increase of thermographically suspect pictures with increasing size, but this was independent of the depth (i.e. the distance from skin surface) of the tumors. The proportion of uncertain but not clearly suspect results was 35% with the infrared telethermovision method, in contrast to 8% with liquid crystal plate thermography. Thermographically non-suspect carcinomas (especially the negative cases with liquid crystal plate thermography) were rich in connective tissue or stroma in most cases. On the other hand, carcinomas with numerous mitoses, large cell nuclei, increased N/C-ratio and large and strongly stained nucleoli predominantly exhibited definitely suspect pictures. The significant correlation between number of mitoses, size and staining of nucleoli and the thermographic results emphasizes that, besides vascularization and altered thermo-regulatory functions, the metabolism of the tumor itself contributes to the temperature differences. The type of growth and histological grading indicate that tumors with unfavourable prognosis preferentially exhibit thermographically suspect results. The use of thermography as a screening method is restricted because of possible false negative results. On the other hand, its additional use is justified in view of the gain in information about the biological situation of suspect alterations of the breast.

Breast Neoplasms↗
PubMed1976

[Diagnosis of breast carcinoma with thermographic methods: tele-thermovision, plate thermography].

The diagnosis of carcinoma of the mamma with the aid of tele-thermovision and liquid-crystal-thermography A review is given on thermographic diagnosis of carcinomas of the mamma with the aid of tele-thermovision and liquid-crystal-thermography. 132 carcinoma cases were microscopically examined with cytomorphological criteria. The microscopic and thermographic results were compared. The thermographic diagnosis "suspicious" is dependent on the diameter of the tumour, the vascularisation, the essential cytomorphological criteria as mitosis, prominence and size of nucleoli as well as deviation of the nucleous/plasma ratio. There was no dependence on the distance of the tumour from the surface of the breast and even on the perifocal infiltration with lymphoid cells. The accuracy rate in diagnosis with liquid-crystal-thermography is about 74%; false negative and false positive results both are about 9%. The accuracy rate for tele-thermovision is about 10% lower. The detection rate of carcinoma stage T1 ranges around 50%.

Breast↗