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Biomedical subjects

G A Feigin

Publications and source records attributed to G A Feigin.

4 recordsLinked to original sources
PubMed1986

Mixed tumor of the mediastinum.

A 36-year-old asymptomatic man was found to have a large middle mediastinal mass on a chest x-ray film. At surgery the tumor was located adjacent to the carina and beneath the aortic arch. It measured 7.0 X 5.0 X 4.0 cm and was well circumscribed and soft, with mucoid areas. The histologic features were those of a benign pleomorphic adenoma of salivary gland origin. This is, to our knowledge, the first reported case of primary pleomorphic adenoma of the mediastinum. We propose an origin from the ectopic salivary gland tissue. We also describe an additional patient in whom ectopic benign salivary gland tissue was found within mediastinal lymph nodes to support our hypothesis.

Adenoma, Pleomorphic↗
PubMed1986

Initial bone marrow findings in multiple myeloma. Significance of plasma cell nodules.

A retrospective review of bone marrow specimens from 235 patients with multiple myeloma and 148 patients with reactive plasmacytosis was performed in an attempt to evaluate the usefulness of bone marrow sections in distinguishing between these conditions. Although the presence of large homogeneous nodules and/or infiltrates of plasma cells in bone marrow sections remains the best criterion for the diagnosis of myeloma, a few specimens (2%) from patients with reactive plasmacytosis also showed this feature. In addition, 26% of the patients with myeloma had bone marrow sections that were considered nondiagnostic in that they lacked recognizable homogeneous nodules and/or infiltrates of plasma cells. Finally, distinguishing multiple myeloma from bone marrow involvement by lymphoplasmacytic lymphomas can be very difficult, if not impossible, based on findings in the sections alone.

Bone Marrow↗