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Biomedical subjects

G A Harrison

Publications and source records attributed to G A Harrison.

205 records · Page 12Linked to original sources

Marital distance and child variability.

The effects of marital distance on the mean and variance of child stature and weight were investigated using the British National Child Development Study data. Children of large marital distance unions had mean values as predicted from mid-parent values and did not exhibit a hybrid vigour effect. However, they did show reduced levels of variability and this effect was most marked at 16 years, although it was also present at 7 and 11 years of age. These results are discussed in terms of large marital distance being associated with high heterozygosity levels, because of geographic variation in gene frequencies.

Adolescent↗

A path analysis of some determinants of infant growth in Khartoum.

The interrelationships between some socioeconomic and behavioural characteristics of mothers and the growth and illness experience of their infants in poor Khartoum townships have been examined by path analysis. For both infant body weight and supine length it is shown that weaning age and illness experience are important determinants of growth. It is also shown that greater maternal income has disadvantageous effects through encouraging early weaning. Most importantly the infants of housewives have later weaning, less illness and greater weight and length at 1 year of age than the infants of mothers with jobs, showing the value of time for caring in the prevailing environmental circumstances.

Adolescent↗

Comparative length and weight growth in Khartoum infants.

First-year postnatal growth of supine length and body weight of a group of Khartoum infants is analysed in terms of the correlation coefficients between birth dimension on the one hand and (1) subsequent distance growth at monthly intervals and (2) the 11-monthly increments on the other. It is shown that the whole of the first-year length growth is dominated by catch-up/catch-down processes which must equally affect the infants. Weight growth is similarly affected, but to a lesser degree and for a shorter time. After 6 months of age some of the influences that determined prenatal weight growth reappear. Using data extracted from fitting growth curves to each individual the correlational analysis suggests a growth pulse in both length and weight, which is responsible for distance catch-up.

Age Factors↗

The impact of caste on the growth of male Sikhs in Punjab, India.

This study is based on a cross-sectional sample of 442 Sikh boys and young male adults who were born in and around the town of Phagwara, in the state of Punjab, India, and stayed there all their lives. The sample comprised Sikh boys at three crucial phases of growth, at 5-6, 10-11 and 15-16 years, and young adults around 18 years of age. The sample comprised three distinct caste groups, viz. Jats, Ramgarhias and Ravidassias, belonging respectively to upper, middle and lower socioeconomic strata of the Sikh community. Differences in stature and body weight are particularly marked around early adolescence, and there is some indication of caste differences reappearing in young adults. In the case of body mass index, however, the differences seem most marked in late adolescence. There is no clear directional pattern to the way skinfolds change, but inter-caste differences become more marked with age. There is a suggestion of continuing growth beyond 16 years of age, and indications that the well-off groups grow more, as compared to the poor groups, during this period. Comparisons of young adults with older groups of the same caste indicate an increase in body weight with age, but smaller stature in the older groups. There is thus evidence for a secular stature increase among present-day Punjabi Sikhs.

Adolescent↗

Effects of early disease on later growth, and early growth on later disease, in Khartoum infants.

Longitudinal data of monthly length and weight measurements, and fortnightly infectious disease records of 167 infants in Khartoum townships, have been examined to determine: (1) whether disease experience in the first 6 months of life is related to growth in the second 6 months and (2) whether growth in the first period is related to disease experience in the second. Using regression techniques to allow for disease measure correlations in the two periods and other environmental factors that are associated with growth and disease, it is concluded that both length and especially weight growth are affected adversely by previous illness. On the other hand there is almost no evidence that early growth is associated with later disease susceptibility.

Body Height↗

Ovarian impairments of female recreational distance runners during a season of training.

This study was carried out to investigate the relationship between the level of training and the impairment of ovarian function among female recreational distance runners, and its reversibility. Thirty-six female distance runners self-recorded, for 7 consecutive days each month, the duration and distance of daily running from October 1989 to May 1990 in Great Britain. During the last 3 months of the survey, saliva samples were taken for progesterone assay and a subsample was measured for body composition. No trend in weight loss was observed over the season of training. Amenorrheic (AM) and oligomenorrheic (Oligo) runners had a significantly lower body mass index than eumenorrheic (EU) and irregularly menstruating (IM) runners. The amenorrheic and oligomenorrheic subjects did not show any rise in progesterone, at any time, during the 3 months of sampling. The eumenorrheic subjects showed evidence of a rise in progesterone, though the mean level was always significantly lower than that of sedentary controls. The most severely impaired runners (AM and Oligo) ran more than EU or irregularly menstruating runners in this sample, had lower body weight, a younger age and had a significantly lower body mass index (BMI). They tended to run faster during training sessions than those with apparently normal menstrual cycle or just irregular periods. It is suggested that low BMI, which is an indicator of body energy stores, reflects the intensity of regular training runs among female athletes with a stable body weight. It is possible that repeated elevations of beta-endorphins or other suppressors of gonadotropin release, secreted above a level of training commonly exceeded by long distance runners, when concurrent with energy restriction, could contribute to impairment of menstrual cycle.

Adult↗

Adductor spastic dysphonia: heterogeneity of physiologic and phonatory characteristics.

Physiologic and phonatory characteristics of 23 subjects with adductor spastic dysphonia were studied, including examination of the laryngeal appearance by fiberoptic nasoendoscopy, neurologic examination, and measurement of phonatory airflow and speaking fundamental frequency. These characteristics displayed considerable heterogeneity among the subjects investigated. Three patterns of laryngeal appearance during phonation were observed: vocal fold adduction, associated ventricular fold constriction, and approximation of the laryngeal inlet. Eight of 13 subjects demonstrated some neurologic abnormality. For the majority of subjects, the airflow demonstrated marked variability during sustained phonation; for different subjects, this variability was observed to be associated with either an oscillatory or irregular airflow pattern. The modal speaking fundamental frequency for the women and men with adductor spastic dysphonia was not significantly different from that for age- and sex-matched controls.

Adult↗