A RARE COMPLICATION OF COUMARIN-CONGENER ANTICOAGULANT THERAPY.
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Biomedical subjects
Publications and source records attributed to G A MAYER.
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In a group of seven physicians engaged on a full-time basis in the anticoagulant unit of a teaching hospital, it was demonstrated that errors occur frequently in the management of anticoagulant therapy and that the incidence of such errors decreases during the course of the physician's training period. Expert supervision and proper organization of the unit permit detection and correction of a high percentage of these errors.
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Viscosity of whole blood and plasma was measured in 258 apparently healthy subjects of both sexes from 5 to 60 years of age, and in 86 patients with unequivocal evidence of chronic coronary heart disease. Children and young healthy females had the lowest viscosity readings. Healthy young and middle-aged males had significantly higher blood viscosity than females. Patients with coronary heart disease had significantly higher blood viscosity values than healthy groups of the same sex. It is suggested that the higher viscosity of whole blood and of plasma is a contributory factor in development of clinical manifestations of coronary heart disease and possibly of the basic vascular lesion itself.
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