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Biomedical subjects

G A Manukian

Publications and source records attributed to G A Manukian.

9 recordsLinked to original sources

[Diagnosis of dilated cardiomyopathy using patient blood serum and myocardial tissue culture].

Based on a study of the interaction of the sera from healthy persons (20), patients with coronary disease (20), rheumatic heart disease (20), myocarditis (20), congestive dilated cardiomyopathy (48) it was established that the sera from dilated cardiomyopathy patients exert an inhibitory effect on the contraction of chick embryo myocardial explants in experiments in vitro. Three grades of the inhibitory effect were detected, depending on the patient's status gravity. The sera from healthy persons and patients with the enumerated cardiovascular diseases failed to produce such an effect.

Adult↗

[Correlations between various cardiometric and functional parameters in dilated cardiomyopathy and alcoholic lesion of the heart (data of roentgenological and echocardiographic studies)].

Volumetric changes of the heart and its left ventricle, as well as myocardial contractility were assessed in 50 patients with dilatation cardiomyopathy (DCMP) and 16 patients with acute alcoholic heart damage (AHD), on the basis of roentgenologic (cardiac shape and volume, left ventricular and aortic pulsation, respiratory volumetric variations, pulmonary circulation) and echocardiographic (end-diastolic size and volume, systolic increment of posterior wall thickness, ejection fraction and left-ventricular shortening) data. Both DCMP and acute AHD were shown to be associated with total enlargement of the heart, diffuse impairment of myocardial contractility, considerably depressed left ventricular pumping function, early congestion in the systemic circulation network coupled with minor roentgenologic signs of congestion in pulmonary circulation.

Adult↗