PubMed Health⌕ Search

Biomedical subjects

G A Natsios

Publications and source records attributed to G A Natsios.

11 recordsLinked to original sources

Recurrent urinary tract infections in men: a role for aberrant bacterial forms?

We studied 11 infected, asymptomatic elderly men who had experienced recurrent urinary tract infections classified as bacterial relapse. These men did not have ileal loop bladders, urethral catheters, suprapubic catheters, or condom drainage. We had to process more than 1,000 urines from men attending the urology clinic to identify the 11 study patients. A positive antibody-coated bacteria immunofluorescence test was detected on the urinary sediments of each of these men. This selective study group was subjected to excretory urography and a 2-week course of antibiotics, in accordance with the results of in vaitro susceptibility tests. Two patients experienced a "cure." Recurrences developed in eight patients (six relapses, two reinfections), and in one patient a superinfection emerged. No pathogenetic role could be attributed to aberrant bacterial forms in this elderly population of asymptomatic men with recurrent, invasive urinary tract infections.

Aged↗

Reliability of a single urine culture in establishing diagnosis of asymptomatic bacteriuria in adult males.

Fifty-nine asymptomatic men without catheters of ileal-loop bladders, who were attending a urology clinic and were incidentally discovered to have 100,000 or more Enterobacteriaceae per ml ("significant bacteriuria") in a clean voided urine sample, were prospectively evaluated. To identify these 59 patients, 5,876 urine samples, collected exclusively from men, had been subjected to quantitation and identification. A repeat urine culture performed on these patients invariably confirmed the results of the initial culture. The reproducibility of a single urine culture containing significant bacteriuria occurred independently of the tissue source of infection, as determined by the antibody-coated-bacteria immunofluorescence test. We conclude that a single urine culture obtained from a cooperative man can establish the diagnosis of asymptomatic bacteriuria.

Adult↗

Septic shock with Micrococcus luteus.

Micrococcus luteus is considered a non-pathogenic saprophyte of human skin and eye. Disease in man caused by this organism is not recorded in medical literature. We present a case of septic shock cause by M luteus. The value of this report is to document the pathogenicity of coagulase-negative staphylococci in patients without valvular heart disease, surgically implanted artifificial prosthetic devices, or polyethylene intravenous catheters.

Aged↗

Two epidemics of pseudobacteremia due to Staphylococcus aureus and Aerococcus viridans.

Two epidemics of pseudobacteremia are reported. The first, due to Staphyloccus aureus, was caused by a physician who had active staphylococcal skin infection and nasal colonization. Because the blood culture system in use at the time was open, and used screw cap bottles, we assume that the physician contaminated the bottles at the time of inoculation. The second outbreak, caused by Aerococcus viridans, was traced to contamination of the blood culture bottle tops as they were received from the manufacturer. We assume that there was inadequate disinfection of the bottle tops by the physicians prior to their use.

Cross Infection↗