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Biomedical subjects

G A Onoprienko

Publications and source records attributed to G A Onoprienko.

At least 19 recordsLinked to original sources
PubMed1995

Treatment of neglected complicated multiple musculoskeletal injuries.

Two hundred eighty-nine patients with multiple bone fractures who had combined impairment of bones and soft tissues were treated from 1960 to 1993 in the authors' institution. All patients were transferred from local hospitals of the Moscow district between several months and 3 years after trauma, and had neglected fractures complicated by dislocations, false joints, and imperfectly united bone fractures. The authors prefer an individual approach to patient treatment and used simultaneous surgical intervention on several bone segments using stable osteosynthesis with AO-POLDI plates and the Ilizarov apparatus. Two-stage operations were done in cases of > or = 3 injured segments. Positive results with restoration of the extremity and its supporting motor systems were obtained in 96% of patients.

Bone Plates↗
PubMed1994

[Osseous stable functional osteosynthesis in the sequelae of bone and joint diseases and injuries].

The method of osteosynthesis association was applied in 1,000 patients with sequelae of diseases and injuries of large joints and bones of the limbs. The results show that stable-functional osteosynthesis with compression plates is a very effective modern method of surgical treatment of patients with serious sequelae of injuries and diseases of the epi-meta-diaphyseal parts of the bone and must be used more extensively in practice.

Adolescent↗
PubMed1991

[Compression arthrodesis of the hip joint].

The results of surgical treatment of grave degenerative dystrophic, traumatic, and inflammatory coxarthroses are discussed. Employment of present-day compression arthrodesis with metal plates designed by the authors helped achieve the union of articulated bones in 97% of 170 patients. This method essentially improves the results of treatment, as against the traditional methods; due to solid fixation of compressed bones the terms of complete rehabilitation of patients are shortened, and no prolonged immobilization with a plaster bandage is necessary.

Acetabulum↗
PubMed1990

[Surgical correction of deformities of the knee joint].

Fifty-nine knee joint deformities were corrected by supracondylar (24 surgeries) and subcondylar (35 cases) osteotomies. Stable fixation with massive submerged implants and Ilizarov's devices promoted a functional management during the postoperative period. Osteotomies are advisable before degenerative dystrophic changes develop in the joint. It should be borne in mind that arthrosis severity and advanced age of the patients are not contraindications against corrective osteotomies if the knee joint mobility is intact. The clinical result depends on the adequacy of the deformation hypercorrection. Despite the absence of an essential regression of degenerative changes in the joint, 35 of the 38 patients evidenced neither pain nor pain alleviation, and improvement of the motor activity in a year after surgery.

Adolescent↗
PubMed1990

[Experience in the use of AO-Poldy implants for supraosseus osteosynthesis].

Having used since 1968 in MONICI the massive metal plates of different configuration and size, developed by Swiss association of osteosynthesis AO and Czechoslovakian company Poldy, the authors summarize the experience of great clinical material. Altogether, there have been operated over 1000 patients with recent and inveterate fractures of tubular bones, pseudoarthroses, incorrectly consolidated fractured fragments, and 603 of them in MONICI. Some of the implants have been adapted by the authors. In doing so, AO principles and techniques were thoroughly observed. Positive results obtained at 96% of patients with grave bone pathology demonstrate expediency of more broad introduction of the mentioned implants for supraosseous osteosynthesis in our country.

Bone Plates↗
PubMed1990

[Several aspects of general biological concept of osteogenesis].

Basing on the literature data and their own findings, the authors present the general biological concept of osteogenesis. The significance of copper compounds (ceruloplasmin) in bone tissue synthesis was revealed; the role of bound iron (transferrin) in the development and maintenance of the inflammatory process induced by opportunistic bacteria and in bone regeneration was confirmed. Analysis of clinical and microbiological findings in the patients with chronic posttraumatic osteomyelitis, coral uroliths, gastrointestinal diseases complicated by cholelithiasis has lead the authors to a suggestion that fecal microcenosis may become one of the criteria for estimating mineral metabolism in the body; the markers of this metabolic disorders are shifted levels of full-value E. coli, Lactobacilli, and, to a lesser degree, of L. bifidum. The presence of E. coli hemolytic variant also essentially contributes to these disorders, when its level surpasses by 2-3 orders the level of this microorganism in normal subjects and in patients whose mineral metabolism is virtually unchanged. When planning multiple-modality treatment of patients with locomotor system defects and disordered salt metabolism, a physician should investigate intestinal biocenosis and prescribe agents to correct the detected disorders.

Bacteria↗
PubMed1989

[Surgical treatment of ununited fractures and pseudarthroses of the femoral diaphysis].

The article analyses experience in the treatment of 125 patients with ununited fractures and pseudarthrosis of the humeral diaphysis by osteosynthesis with massive compressing metal plates. The possibility of creating the necessary reserve of mechanical stability at the expense of the massive plates and strained fixation allows immobilization in a plaster cast to be avoided in most cases and early motor rehabilitation of the patients to be undertaken. The results were positive in 96.8% of cases, which makes it possible to consider the method to be sufficiently effective in the management of fractures of the humeral diaphysis and their sequelae.

Adult↗
PubMed1988

[Immuno-microbiological characteristics of posttraumatic osteomyelitis].

Anti-infectious resistance factors and microflora in the focus of inflammation have been studied over the course of chronic posttraumatic osteomyelitis in adults. This disease is associated with elevated levels of leukocytes, lymphocytes, IgG, normal or elevated levels of IgA and lysozyme in the peripheral blood. The data obtained in the immunological examination of chronic osteomyelitis patients indicate that such patients fall into two groups: with and without pronounced IgM deficiency. Changes in microbiological and immunological characteristics vary in different groups. A detailed characterization of microflora in the focus of inflammation over the course of the disease in all patients and in individual groups of patients is presented, and the dynamics of anti-infectious resistance factors is shown to reflect changes in microflora in the focus of lesion, which is manifested by changes in immunoglobulin levels corresponding to primary (the initial IgM level being normal) and secondary (a low IgM level) immune response.

Adult↗