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Biomedical subjects

G A Pedachenko

Publications and source records attributed to G A Pedachenko.

15 recordsLinked to original sources

[Emergency medical aid to patients with craniocerebral trauma in the prehospital period].

On the basis of analysis of more than 5000 observations of the sufferers admitted to the Kiev Research Institute of Neurosurgery for acute craniocerebral trauma from 1975 to 1991, quality of giving medical aid at the prehospital period was studied. Of most importance, are the measures directed at struggle against respiratory disorders, disturbances in cardio-vascular activity, shock, hemorrhage.

Acute Disease

[Clinical aspects, diagnosis and treatment of cranio-thoracic injuries in patients of different age].

The comparative analysis of the clinical manifestations and informative value of the adjuvant methods of investigation in 125 patients with ++cranio-thoracic injuries and 53 patients with isolated craniocerebral trauma was carried out. This permitted to define more precisely the possibilities of the methods of neurosurgical diagnosis and find the optimal methods for the treatment of patients of different age with ++cranio-thoracic injuries.

Adult

[Therapeutic tactics in treatment of patients with cranio-cerebral injury and alcoholic intoxication].

Case-histories of 1077 victims of cerebro-cranial injuries, 38 per cent of whom were admitted in the state of alcoholic ebriation, were analyzed. Alcoholic ebriation was found to materially change the clinical picture of the cerebro-cranial trauma, simulating, sometimes, a picture of a traumatic brain lesion. Curative measures aimed at the treatment of the traumatic lesion of the brain were applied in a complex set, depending upon the nature and the severity of the cerebro-cranial injury, the phase (stage) and degree of alcoholic ebriation.

Alcoholic Intoxication

[The characteristics of closed craniocerebral trauma in older persons].

It is shown that in the recent 2 decades the incidence of craniocerebral trauma increased from 4.8 to 7.2% among old-aged individuals and from 53 to 72% in the group of patients over 60. The dynamics of changes in the clinical course of mild craniocerebral trauma in 21% of old-aged patients were marked by secondary acute cerebral circulatory disorders which often led to a fatal outcome. Mortality rate in craniocerebral trauma at old age was 52.3%.

Aged

[Bilateral traumatic subdural hematomas].

The authors studied 57 verified cases of bilateral traumatic subdural hematomas (BTSH) 36 of which were acute, 4 subacute, and 17 chronic. The patient's ages ranged from 15 to 84 years. The clinical picture of BTSH is made up of general cerebral, primary-focal, and dislocation symptoms. Computerized tomography, serial cerebral angiography, and trephinations formed on both sides help in detection of BTSH. Simultaneous opening of the dura mater on both sides with slow evacuation of the contents of the hematomas is an important stage of surgical intervention in BTSH.

Accidents, Home

[Craniocerebral trauma and stroke].

It was demonstrated from analysis of 685 cases that craniocerebral injury is attended by the development of secondary acute disorders of cerebral circulation in 8.9% of cases. Cerebral apoplexy is encountered in craniocerebral trauma 4-5 times more frequently (in 25% of cases) among patients with arterial hypertension and 2-2.5 times more frequently (in 12% of cases) among those with diabetes mellitus than in patients with a nonacerbated somatic anamnesis (in 5.4% of cases).

Adolescent

[Cryosurgery of cerebral arteriovenous aneurysms].

The use of stereotaxic cryothrombosis is sparing and sufficiently safe for the management of arteriovenous aneurysms of the brain. On the basis of experience in performing 21 operations on 15 patients, groups of patients for whom the method is recommended are distinguished (with an aneurysm no larger than 6 cm in diameter and up to 35 cm3 in volume). The method is especially promising in the treatment of small deep lying anteriovenous aneurysms. In large aneurysms the considerable blood flow makes it impossible to produce a sufficient hypothermal effect.

Adult

[Clinical picture, diagnosis and treatment of metastatic melanoma of the brain].

The morphological and clinical features of the disease were studied in 73 patients with malanoma metastasis to the brain. A morphological examination revealed predominance of the epithelial-like structure of the tumors over fusocellular, infiltrative growth of metastases in the brain, and many newly formed defective vessels in the metastatic tumors which were conducive to frequent hemorrhages. The clinical picture of the disease was marked by the predominance of general cerebral symptoms over focal. With regard to the diagnosis, much importance is attached to medical history and peculiarities of the clinical manifestations of the disease and to the results of an auxiliary examination (radiocontrast, electrophysiological, etc). Treatment of patients with melanoma metastases in the brain should be combined and should include, whenever indicated, surgical intervention, hormonotherapy, radiotherapy, and chemotherapy.

Adolescent