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Biomedical subjects

G A Tkacheva

Publications and source records attributed to G A Tkacheva.

At least 37 records · Page 2Linked to original sources
PubMed1983

[Parathyrin content of lung cancer patients undergoing surgical and chemotherapeutic treatment].

Parathyrin concentration was determined in lung cancer patients prior to and after operation by using a radiological method. A preoperative elevated level of parathyrin was noted in 60.4% of the patients. Radical surgery resulted in the return of the parathyrin level to normal, and toxic effects caused by chemotherapy were accompanied by its sharp increase. A similar increase in the parathyrin level attends generalization of a tumor process.

Adenocarcinoma↗
PubMed1982

[Blood plasma content of hormones and carcinoembryonic antigen in tumorous and nontumorous disease of the thyroid].

Radioimmunological tests for carcinoembryonic antigen, antibodies to thyroglobulin, thyrotropin of pituitary, thyroxin and triiodothyronine were run in healthy subjects and patients suffering from cervical thyroid and extrathyroid neoplasms, e. g. nodular goiter, adenoma, cancer, chronic thyroiditis, lymphadenitis, neurinoma, hemangioma and thyrotoxicosis. The thyroid was scanned with 131I or 99mTcO4 in all cases. Scanning of thyroid in the first stage of screening for malignant tumors because "warm" or "hot" foci in scanograms of cases of malignant nodes are very rare. In patients with "cold" thyroid nodes, detection of thyroglobulin antibodies points to thyroiditis since such antibodies are not found in all other cases. None of the indices showed any differences in cases of nodular goiter and "cold" adenoma. Coefficient sTTH/bTTH (ratio of thyroliberine-stimulated level of pituitary thyrotropin to basal one) is decreased, while coefficient (Formula: see text) and blood plasma level of carcinoembryonic antigen are increased in patients with thyroid cancer as compared with benign tumors.

Adenoma↗
PubMed1982

[Calcitonin and parathyrin in the blood serum of cancer patients].

A comparative radioimmunologic study of changes in the ratio of calcitonin and parathyroid hormone secretion was carried out in healthy controls (young and older than 40 years), patients with benign tumors, inflammatory processes and malignancies of the stomach, kidney, breast, prostate and lung. A significant increase in the "calcitonin index" (ratio of molar concentrations of calcitonin and parathyroid hormone) was established in patients with cancer of the breast, prostate and skeletal metastases of lung cancer, irrespective of the presence of primary tumor. This index is irrelevant in cases of gastric and renal carcinoma and cannot be used a indication of skeletal dissemination because of the predominant level of parathyroid hormone secretion.

Adult↗
PubMed1982

[Carcinoembryonic antigen in lung cancer patients].

Radioimmunoassay of carcino-embryonic antigen was conducted in lung cancer patients before and after surgery. Elevated concentrations of the antigen before operation was registered in 84.8% of cases. Antigen levels returned to normal after radical removal of tumor and rose sharply as a result of chemotherapy toxicity. A similar pattern of changes in carcino-embryonic antigen level was observed in cases of disseminated and recurrent cancer.

Adult↗