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Biomedical subjects

G A Zubkova

Publications and source records attributed to G A Zubkova.

17 recordsLinked to original sources

[The surgical treatment of congenital heart defects in neonates and infants without using invasive study methods].

Echocardiographic analysis of 328 closed operations for aortic coarctation, patent ductus arteriosus, and congenital heart disease of the blue type with lower pulmonary flow in infants of the first year of life revealed diagnostic errors in 6 (2%) patients, this resulting in death of two patients. Surgery for congenital heart disease, which is based on the echocardiographic data without invasive diagnostic methods, requires proper patient selection. Quantitative two dimensional echocardiography allowed for higher accuracy of the preoperative diagnosis. Introduction of Doppler echocardiography made it possible to perform successful operations with assisted circulation in 16 patients for ventricular septal defects, atrial septal defect, transposition of great arteries, atrioventricular communication.

Echocardiography↗

[Surgical procedure in repeated operations on the mitral valve].

The experience in repeated operations on the mitral valve is generalized and the results of 340 repeated closed mitral commissurotomies and 124 operations performed under conditions of extracorporeal circulation are analysed. Hospital mortality in open operations is still rather high (20%), whereas the stability of good results in follow-up periods of up to 5 years is 53.9%. At the same time, the results of repeated closed operations are quite acceptable; low hospital mortality (4.7%), relatively satisfactory stability of good results (55.3% in follow-up periods of up to 10 years). The authors believe that a differentiated approach to the choice of the method for repated operations on the mitral valve is necessary.

Extracorporeal Circulation↗

[Angiocardiographic and echocardiographic diagnosis of complete transposition of great vessels in association with pathology of the aorta].

The article analyses experience in the diagnosis of a pathological condition of the aorta in complete transposition of the great vessels (CTGV) in infants. Pathology of the aorta was revealed in 9 (2.6%) of the 350 patients who were examined. Six patients with CTGV had coarctation of the aorta (CA), 2 had subaortic stenosis, and one patient had complete interruption of the arch of the aorta. Our experience provides evidence that two-dimensional echocardiography allows the region of the thoracic aorta to be located from a suprasternal or a high right parasternal approach. Subaortic stenosis was diagnosed in 2 patients during autopsy. Retrospective analysis of the echocardiograms and angiocardiograms revealed characteristic signs of subaortic obstruction. Absence of the continuity of the arch and descending aorta is an echocardiographic sign of interruption of the arch of the aorta which was recognized retrospectively only after angiocardiography. Right and left ventriculography must be performed for precise anatomical diagnosis of CTGV with an intact interventricular septum combined with coarctation of the aorta. In patients with concomitant interventricular septal defect this examination is supplemented by antegrade and retrograde aortography from the ascending aorta to exclude patent ductus arteriosus and for better visualization of CA. Catheterization of all heart cavities, right and left ventriculography, aortography, and pulmonary arteriography must be carried out in all patients with total interruption of the continuity of the arch of the aorta.

Angiocardiography↗

[Evaluation of the force loads on the elements of artificial heart valves from the results of processing echocardiograms].

Approaches to further improving the valve prosthesis construction greatly depend on the knowledge of the physical load affecting the elements of artificial cardiac valves that operate in the human organism. An analysis of echocardiograms is given. They were recorded in the patients with implanted artificial ball heart valves, type MK4-2.25. The design values for the force of the ball impact against the valve shell are presented. The echocardiogram analysis revealed a phenomenon of the fibrotic ring deformation under the ball action on the valve shell and the degree of this deformation has been determined.

Biomechanical Phenomena↗

[Anatomic correction of transposition of the great arteries in infants:experience of the first 10 operations].

In the period March 1992 to January 1993, ten patients with transposition of great arteries (TGV) whose age ranged from 9 days to 8 months and body weight 3.2 to 7.2 kg were operated on using the arterial switch. A single-stage anatomic correction was made in 2 patients with patent arterial duct, 4 with ventricular septal defect (VSD), one with multiple VSD. Three patients with common TGA underwent correction in 2 stages: arterial switch followed prior constriction of the pulmonary artery switch followed prior constriction of the pulmonary artery and subclavian-pulmonary anastomosis. In all cases of single VSD, it was closed with a flap made from the Gore-Tex material. In the whole series of operations, 2 patients died: one being on the operating table due to anesthesiological errors, the other due to coronary blood flow disorder 3 hours after surgery. Six of the 8 discharged patients were followed 3-8 months after surgery. Two patients needed digitalis. No sign of myocardial ischemia was detected in antibody. All the patients were found to have normal left ventricular pump function. These surgeries are the first in our country and so our little experience may be of interest for national specialists.

Arteries↗