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Biomedical subjects

G Albert

Publications and source records attributed to G Albert.

17 recordsLinked to original sources

[Use of pit and fissure sealants in private practice: the Quebec situation].

This paper presents data collected in March of 1989 from a sample of dentists practicing in the province of Quebec. A survey was mailed to dentists in order to determine to what degree sealants are used and the various characteristics relative to the dentists in question. Other questions related to how dentists obtained information about sealants, the difficulties encountered with their application and the problems relative to their use by the dental profession. The results indicate that nearly three quarters of Quebec dentists use sealants at least sometimes. This level of usage is comparable to American findings. A dentist is more likely to use sealants, if he is a recent graduate, a female dentist, and in a child-oriented group practice. A high proportion of dentists (2/3) use sealants selectively (in less than 25% of their patients). According to the dentists surveyed, the main obstacle to using sealants is the lack of coverage by the government dental program and the public's ignorance of the benefits of sealants. Most dentists who admitted never trying sealants, reported that they simply preferred to place an amalgam filling. In general, dentists knew the indications for sealants and had a positive attitude relative to their use.

Attitude of Health Personnel

[In vivo retention of KOH soluble and firmly bound fluoride in demineralized dental enamel].

Cylindrical enamel blocks with initial carious lesions were treated for one hour with Duraphat or Fluor-Protector. After removal of the fluoride varnishes the enamel blocks were kept in the mouths of 3 probands for 5 days. Plaque was allowed to accumulate on half of the enamel cylinders, while the other half was kept clean. Part of the enamel cylinders were retained as fluoridated controls. Compared with Duraphat the application of Fluor-Protector resulted in a significantly higher uptake of KOH soluble and firmly bound fluoride. During the 5 days of the experiment the amount of KOH soluble fluorides decreased in both groups. In the presence of plaque the fluoride loss was higher. The amount of firmly bound fluoride increased both in the plaque covered and in the clean enamel. The durable cariostatic effect of fluoridated varnishes seems to be due to the slow dissolution of Ca F2-like precipitates on the enamel surface and the concomitant fluoride uptake in the underlying demineralized enamel.

Dental Caries

The immunohistochemical distribution of collagens type IV, V, VI and of laminin in the human oral mucosa.

The distribution of collagens type V (form AB2) and VI was investigated on cryostat sections of normal human oral mucosa by indirect immunofluorescence. For comparison, antibodies to fragments of type IV collagen and laminin were also used to delineate basement membrane containing structures. All antibodies used were raised against human proteins. Type V collagen appeared as a microfibrillar structure throughout the interstitium, apparently touching but not being present within epithelial or vascular basement membranes. Microfibrils in blood vessel walls were limited to the intimal layer. Pericellular areas were not specifically stained. Type VI collagen appeared as an almost amorphous stromal structure becoming more prominent and more fibrillar in the upper connective tissue papillae. Intense staining was observed in the media of blood vessels and around smooth muscle cells. A possible role of type VI collagen in tissue stabilization may be expected from this ubiquitous and abundant distribution. The findings identify types V and VI collagen as important structures in the oral mucosa and serve as a basis for understanding morbid changes.

Antibody Specificity

Oral and dental development in X chromosome aneuploidy.

Though frequently noted, orofacial anomalies in poly X syndromes have been seldom reviewed. In a study of patients with an X chromosome aneuploidy (XXXXX, XXXX, XXXXY, XXXY) the following facial and dental defects were found to be characteristic features of these syndromes: mainly bifid uvula and macroglossia, enamel defects, dental taurodontism and abnormal roots. These observations are discussed in the light of the possible role of X-linked genes.

Adolescent

[Histometric studies of functional assessment of the parathyroid glands in healthy and sick cattle].

--Weights and mean nuclear surfaces of external epithelial bodies were examined in 53 clinically intact young fattening bulls, 49 clinically intact dairy cows, 55 young fattening bulls slaughtered on account of emergency mainly for osteolamacia and rickets, and 50 cows that had died of various diseases. --Absolute parenchymal levels were found to increase along with growing age. --In young fattening bulls, epithelial bodies lost weight and nuclear surface along with severity of pathological bone changes. --Epithelial bodies in cows and young fattening bulls feeding primarily on silage were more active than those of animals feeding to a larger extent on meadow hay or kept grazing. --No signs of increased activity of epithelial bodies were recordable from animals with osteomalacia or those close to parturition. --All results so far derived from the above studies seem to suggest that, with the present regime of cattle feeding, calcium deficit or phosphate excess are not involved in the development of skeletal diseases. The findings so far obtained in the context of epithelial bodies have confirmed the contrary to the effect that calcium excess and phosphate deficit have remained to be the major causes of skeletal diseases.

Animals