Synthesis and pharmacological activity of (bicyclo [2.2.1] hept-2-ylidene)acetic acid amides and 2-(bicyclo [2.2.1] hept-2-ylidene)ethanamines.
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Biomedical subjects
Publications and source records attributed to G Alise.
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The A. by a series of experimental works have shown that an association of total bacteria antigens (SPRE) administered in the rabbit vai intramuscular route or by inhalation is able to cause the appearance of serum specific antibodies and to have a significant protective action.
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The antibronchospastic value of the triple association adrenaline (1) + atropine (0,3) + papaverine (3) has been documented experimentally. Comparative investigations have been carried out with isoprenaline, metaproterenol, terbutaline and salbutamol. Toxicological and pharmacodynamic studies were done in the cardiovascular system and in vitro on certain muscles.
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Experimental research has shown that inosine in doses of 100-500 mg/kg has a protective effect with respect to various experimentally induced myocardiopathies.
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