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Biomedical subjects

G Alvine

Publications and source records attributed to G Alvine.

3 recordsLinked to original sources
PubMed1996

Hibernoma.

Hibernoma is a rare, benign soft tissue tumor composed of brown fat. A 42-year-old white man presented with an enlarging soft tissue mass located in his left medial thigh. This was evaluated radiographically by CT as well as MR imaging. An open biopsy revealed a hibernoma. The mass was subsequently excised in its entirety, maintaining a cuff of normal tissue. The patient has done very well postoperatively. Although nearly 100 cases have been reported, this case is presented to review the clinical and pathological presentation of this tumor and to describe its MR imaging characteristics.

Adult↗
PubMed1996

Changes in the structural properties of peripheral nerves after transection.

Changes in peripheral nerve structural properties after transection were measured weekly for 5 weeks in the distal stump of the sciatic nerve in 50 Sprague-Dawley rats. Each week after transection, the distal stump of the transected nerve showed increased stiffness when compared to intact nerves. Linear elastic stiffness reached a maximum at weeks 1 and 2 after transection, when the transected nerves were 15% stiffer than the contralateral control sides. Toughness was also increased and reached a maximum at week 4 with a 50% difference between values for experimental and control sides. Overall failure load was between 21% and 27% greater, peaking at week 3. An increase in stiffness of the distal stump would result in increased tension at the suture line, as the nerve gap is overcome when performing a delayed neurorraphy. These data suggest, with respect to structural properties, that an end-to-end repair should be carried out at the time of injury; after only 1 week, significant stiffness in the distal segment of the nerve developed, which should result in an increase in tension at the repair site.

Animals↗