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Biomedical subjects

G Antonelli

Publications and source records attributed to G Antonelli.

At least 145 records · Page 8Linked to original sources

Diagnosis of aneurysm of the thoracic aorta. Comparison between two non invasive techniques: two-dimensional echocardiography and computed tomography.

In order to assess the respective values of two-dimensional echocardiography (2D echo) and computed tomography (CT) in the evaluation of aneurysms of the thoracic aorta, 14 patients with angiographically proven aneurysms of the thoracic aorta (three of which were dissecting aneurysms) were studied. The entire thoracic aorta was visualized in 10/14 patients by 2D Echo and in all patients by CT. An intimal flap was recognized by 2D echo in each case with a dissection whereas such a recognition was never possible with CT. CT identified calcification of the wall of an huge aneurysm of the ascending aorta in one case and a thrombotic stratification in the lumen of the descending thoracic aorta in another case; both abnormalities were missed by echocardiography probably because of inappropriate gain setting. In conclusion, 2D Echo and CT are both useful in the evaluation of aneurysms of the thoracic aorta; 2D echo appears to be superior in the recognition of an intimal flap due to dissection whereas CT allows a better recognition of the configuration, extension and tissue modifications of the aneurysm.

Adult↗

[Abnormal intracavitary dynamic echoes. II. In vivo study].

UNLABELLED: Dynamic intracavitary echoes (DIE's) suggesting regional stasis of blood, were detected in 17 patients (pts) (6 with mitral stenosis, 1 with mitral prosthesis, 5 with congestive cardiomyopathy, 5 with left ventricular aneurysm). DIE's were observed in the left atrium in all pts with mitral stenosis and in the patient with a prosthetic valve, in the left ventricle in the remaining pts. In 5 pts a thrombus was detected in the cardiac chamber in which DIE's were observed. In 4 pts direct inspection (at surgery or autopsy) of the cardiac chamber in which DIE's were detected revealed the presence of non-coagulated blood. All pts with DIE's in the left atrium were in atrial fibrillation. In one case with mitral stenosis DIE's disappeared after commissurotomy. IN CONCLUSION: DIE's suggesting regional stasis of blood may be detected in pts with clinical conditions characterized by slow cardiac flow; this phenomenon may be caused by red cell aggregation occurring in those conditions.

Adolescent↗

Two-dimensional echocardiographic evaluation of aneurysms of the descending thoracic aorta.

To determine the ability of two-dimensional echocardiography (2-D echo) to detect aneurysms and dissections of the descending thoracic aorta (DTA), we studied 15 patients, five with proved DTA dissections (group A) and 10 with proved aneurysms without dissection (group B), using 2-D echo in three recording positions: precordial, suprasternal and a modified apical. The DTA was visualized in 14 of 15 patients (93%); in each patient in group A, an intimal flap was recognized (in two patients only by the apical approach and in one patient by all approaches). The DTA was visualized in nine of 10 patients in group B; in each patient, the internal dimension of the DTA was enlarged (25-43 mm/m2). In one group B patient, aortic dissection was erroneously suspected because spurious echoes were present in the lumen; in another patient, 2-D echo failed to demonstrate a thrombotic stratification in the enlarged lumen. We conclude that 2-D echo using all available approaches appears to be a reliable technique for evaluating dissections and aneurysms of the DTA.

Adult↗

Ileum-like congenital elongation of the proximal descending aorta.

A case of extraordinary congenital elongation of the proximal descending aorta giving origin to multiple aortic loops, packed in the left-postero-superior mediastinum, is presented. Clinical findings, that is, mid-late systolic ejection murmur, a delayed peak of the femoral pulse, blood pressure in the legs slightly lower than in the arms, were considered noncontributory from the diagnostic point of view, since they may also be present in mild aortic coarctation and in aortic kinking. Chest roentgenogram and fluoroscopy showing 2 pulsating masses protruding to the left of the proximal descending aorta suggested the presence of a more complex aortic malformation. Only angiography provided a correct diagnosis and detected some associated abnormalities as well.

Adult↗

Chronic juvenile AV nodal dysfunction associated with mitral valve prolapse.

The prevalence of atrioventricular (AV) conduction disturbances amongst patients with mitral valve prolapse is higher than may be expected by chance, thus implying the existence of a true association. The main clinical and electrophysiologic findings in 4 patients with mitral valve prolapse showing chronic AV conduction disturbances are presented. Supra-His localization, mild and variable degree of impairment, regression upon Atropine administration, apparent absence of progression, are common features of these disturbances. The most likely mechanisms considered are an AV node developmental abnormality or an AV nodal artery running in contact with the border of the mitral annulus and thus impaired by the abnormal dynamics of the mitral valve.

Adolescent↗

[Mitral valve prolapse and the ventricular pre-excitation syndrome (author's transl)].

One of the most important clinical aspects of the mitral valve prolapse syndrome is the high incidence of arrhythmias. Some recent reports on the association of mitral valve prolapse with ventricular pre-excitation may be relevant to the understanding of such arrhythmias. In order to evaluate the clinical relevance of this association, all patients with proven idiopathic mitral valve prolapse who came under our observation during the last twelve months, were submitted to careful electrocardiographic examination with the aim of detecting even subtle degrees of pre-excitation. His bundle recording and programmed atrial stimulation were performed if there was any suspicion of a delta wave. The association with ventricular pre-excitation was proved in 6 out of 41 examined cases. The main clinical, phonocardiographic, echocardiographic, angiographic and electrophysiologic data, as well as the familial study of these cases, are presented. The need for electrophysiologic study in some cases with doubtful electrocardiographic pattern is pointed out. While previous reports only described cases with left-sided accessory pathways, examples of right-sided pathways are presented in our series. The high incidence of mitral valve prolapse, and especially of pre-excitation syndrome and arrhythmias in the familial study, suggests that the association is not an occasional one. The detection of ventricular pre-excitation in cases of mitral valve prolapse complicated by recurrent tachy-arrhythmias may be of practical importance for an appropriate therapeutic approach.

Adult↗