Biological activities of a combination of medroxyprogesterone acetate and ethinyloestradiol.
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Animals↗
Biomedical subjects
G Arcari
Publications and source records attributed to G Arcari.
[Influence of a trophic collyrium on the experimental corneal wounds].
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Animals↗
Studies on a compound antagonistic to 5-hydroxytryptamine.
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Animals↗
[The influence of steroids on central regulatory mechanisms].
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Anabolic Agents↗
[Enzymo-histochemistry of the fetal adrenal and testicle in normal and hypophysectomized rats].
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Adrenal Glands↗
Antinociceptive, prolactin releasing and intestinal motility inhibiting activities of dermorphin and analogues after subcutaneous administration in the rat.
A series of analogues and shorter homologues of dermorphin (DM), a frog skin heptapeptide with potent morphine-like activity, have been assayed in the rat after subcutaneous (SC) administration at the screening dose of 4 mg/kg. The effects taken into account are: analgesia (tail-pinch test), stimulation of prolactin (PRL) secretion, and inhibition of gastro-intestinal (GI) motility (charcoal meal transit). Effective doses were calculated for the most active compounds. The potency of DM (H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2) in the different tests was: tail-pinch: ED50 = 0.83 mg/kg; PRL release: ED100 = 0.3 mg/kg; inhibition of GI motility: ED30 = 1.8 mg/kg.
Animals↗