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Biomedical subjects

G Astorga

Publications and source records attributed to G Astorga.

18 recordsLinked to original sources

[Interstitial pulmonary involvement in rheumatoid arthritis. Analysis by bronchoalveolar lavage].

We analyzed the results of bronchoalveolar lavage (BAL) in 14 patients with Rheumatoid Arthritis. Ten patients had total cell counts above 10 x 10(6)/100 ml and or more than 10% lymphocytes in differential counts. 40% of patients with normal clinical findings on pulmonary examination and normal A-a O2 gradients had abnormal BAL findings. These findings support the theory that pulmonary fibrosis in patients with RA may start with alveolitis, probably a lymphocytic type in 60% of cases. BAL may help early diagnosis and treatment monitoring.

Adult

[Active rheumatoid arthritis: effect of dietary supplementation with omega-3 oils. A controlled double-blind trial].

We evaluated the effect of dietary supplementation with eicosapentaenoic acid in 8 patients with active rheumatoid arthritis. An appropriate placebo was given in a randomized double blind fashion to 8 control subjects. After 12 weeks of therapy a significant improvement in prehensile function was detected in patients receiving active treatment, other clinical parameters remaining unchanged. No significant side effects were detected. A larger trial may help define a possible therapeutic role for omega-3 fatty acids in patients with rheumatoid arthritis.

Adult

[Patients with primary anterior uveitis. Determination of circulating immune complexes].

The level of circulating immune complexes (CIC) in 31 patients with primary anterior uveitis was determined by an ELISA method (C1q in solid phase). In addition, we measured antinuclear antibodies (ANA), HLAB 27, C3 and C4. Increased levels of CIC were found in 38% of patients (Group I), the remainder had normal levels (Group II). Positive ANA were found in 33% of patients in Group I and 26% of patients in Group II. The clinical findings and course of uveitis was similar in both groups. Chronic uveitis was associated to greater levels of CIC as compared to recurrent uveitis among patients in Group I (p less than 0.0001). Also, moderate sequelae from uveitis were associated to higher CIC levels.

Adolescent

[Headache of cervical origin].

We studied 40 patients with cervical spine disease who had headache (Group A) with 40 patients with disease and no headache (Group B). In addition to clinical and radiologic evaluation, 24 patients in group A and 27 in Group B had electromyographic study, which was normal en 18 of the former and 4 of the latter group. Abnormal neurologic findings were present only in Group B (37% of patients). Alterations of the cervical spine were more pronounced in Group B. These findings suggest that headache is not related to cervical spine disease and may be caused by other factors such as inadequate posture, brisk movements of the neck and emotional and psychologic disturbances.

Adult