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Biomedical subjects

G B Berliner

Publications and source records attributed to G B Berliner.

At least 19 recordsLinked to original sources
PubMed1997

[Late complications of combined therapy of lymphogranulomatosis].

Basing on the results of follow-up of 212 lymphogranulomatosis patients in long-term remission, the authors have identified most frequent and serious complications. Contribution of different treatment components to development of these complications is specified. Signs of mono- and polyorganic lesions due to combined therapy are described, recommendations on the follow-up and prevention of the complications are provided.

Adult↗
PubMed1994

[The characteristics of iron metabolism in B12-deficient anemias (an evaluation of the functional status of megaloblastic erythropoiesis)].

The review of the literature data and the evidence obtained on 85 own patients with B12-deficiency anemia concerning iron metabolism underlie 3 variants proposed by the authors: pronounced manifestations of secondary sideroachresia before B12 therapy, utilization iron deficiency upon B12 introduction, dimorphic anemia (development of megaloblastic erythropoiesis in prior iron deficiency). The causes of megaloblastic erythropoiesis incompetence (slow rate, hemolytic component, secondary sideroachresia) are discussed.

Anemia, Iron-Deficiency↗
PubMed1991

[A severe course of autoimmune thrombocytopenia and the procedure for its treatment in systemic lupus erythematosus].

The authors describe three comparatively rare cases of extremely severe symptomatic autoimmune thrombocytopenia associated with systemic lupus erythematosus. The use of glucocorticoids in large doses and in two cases of splenectomy turned out ineffective. The next therapeutic measures are suggested in the following succession: glucocorticoids----cytostatic drugs (vincristine)----splenectomy to be performed only in special cases.

Acute Disease↗
PubMed1987

[A case of a long-term course of Brill-Symmers disease without active antineoplastic therapy].

The paper is concerned with a case of Brill-Symmers' disease started with the thrombocytopenic syndrome relating to hypersplenism. After splenectomy the first benign stage of disease without eradication therapy lasted over 10 years. Signs of immunological incompetence (signs of secondary infection) and recurring immune thrombocytopenia were noted in that period. A regular use of glucocorticoids and antibiotics resulted in the improved condition. The development of the second stage of disease (malignant diffuse lymphoma with the involvement of the internal organs) was fast resulting in the patient's death.

Adult↗
PubMed1986

[Results of splenectomy with polychemotherapy in the treatment of 15 chronic myeloid leukemia patients].

The results of splenectomy followed by chemotherapy are analysed. Fifteen patients with chronic myeloid leukemia (CML) were entered into the study. The maximal survival of one of the patients subjected to splenectomy was 102 months. The authors come to the conclusion that it is desirable that CML patients should be subjected to splenectomy after preliminary preparation (chemotherapy and chemoprotectors) at the early stages of the illness, which is to be followed by monochemotherapy. Provided the latter is unsuccessful, the change over to polychemotherapy similar to the treatment protocols for myeloid leukemia is suggested.

Adult↗
PubMed1985

[Use of cytosar (cytosine arabinoside) in the control of herpetic complications in patients with acute leukemia and lymphogranulomatosis].

The authors report the use of the cytostatic drug cytosar in the control of herpetic complications in patients with acute leukemia and lymphogranulomatosis. A distinct effect was obtained as a result of intravenous drip of cytosar in a dose of 0.03-0.05 g for 2 days. It is desirable that cytosar therapy may be instituted within the first days of the development of herpetic infection.

Adolescent↗