A micromethod for the quantitative determination of beta-aminoisobutyric acid.
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Aminoisobutyric Acids↗
Biomedical subjects
G B Gerber
Publications and source records attributed to G B Gerber.
Biochemical and autoradiographic studies on DNA metabolism in vitamin E-deficient hamsters.
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Bone Marrow↗
Relation between number of hemopoietic stem cells in newborn mice and their radiosensitivity.
Fractionation of a radiation exposure causes greater damage in newborn mice than a single application since it induces radioresistant foetal hemopoietic stem cells to differentiate prematurely to more radiosensitive adult ones. In the present investigation, it was studied whether other agents that give rise to extensive stem cell destruction also lead to such a change in radiosensitivity. Indeed, treatment with cytostatic drugs which reduces the number of spleen colony forming units (CFU-s) and total cells also diminished the D0 value of the surviving cells 3 days later. Adriamycin was most effective in causing damage to hemopoietic stem cells and in inducing micronuclei in bone marrow; it also had the most marked action on the D0 of the surviving stem cells.
Aging↗
Biochemical indicators of radiation damage: perspective and review.
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Adrenal Cortex Hormones↗
A sensitive and specific determination of gamma aminobutric acid in brain.
A sensitive and specific method for the determination of gamma aminobutyric acid in small (30 mg) brain samples is described. It is based on preparation of the dansyl-butyrolactam (DBL), subsequent separation by thin layer chromatography and measurement of fluorescence after elution. Recovery is checked by routinely adding 14C labelled GABA.
Aminobutyrates↗