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Biomedical subjects

G B Glasenapp

Publications and source records attributed to G B Glasenapp.

10 recordsLinked to original sources

[Carcinoma of the hypopharynx as late sequel to x-ray exposure (author's transl)].

Two cases of x-ray induced carcinomas of the hypopharynx after radiation treatment of a struma some decades ago are described. Therefore widespread application of x-ray radiation in the treatment of benign tumours should be avoided. On account of a serious local damage of the skin in both patients the administration of an immoderate dosage must be supposed. This observation seems to be especially remarkable because these patients have been irradiated in the forties which is much earlier than other x-ray induced carcinomas reported in the literature.

Aged↗

[The problem of tracheal stenosis following laryngectomy (author's transl)].

The striking frequency of tracheal stenoses following laryngectomy gave reason for considerations on the typical causes. In our case-materials 9 tracheal stenoses were observed following 229 laryngectomies during the period from 1952 to 1972. Two of these cases represent typical stenoses produced by pressure. Within a short period of time, from 2 days up to 6 months after operation the 7 remaining cases represented marked tracheal stenoses with the mucosae showing no signes of irritation. These stenoses had been registered since 1965 only, i.e. after the introduction of the general application of insufflation anesthesia in every case of laryngectomy at our clinic. These observations gave reason for supposing that the procedure of anesthesia had to be seen as responsible for the development of tracheal stenoses. Under unfavourable circumstances during operation, even if the tube is inserted for a short period of time the anemising pressure effect of the cuff of the tube might - beside other wellknown factors - produce damages on the tracheal wall.

Aged↗

[A case of industrial origin of laryngeal carcinoma (author's transl)].

The Growing importance of industrial noxae for carcinogenesis will, in the course of further progressive mechanization and industrialization, suggest an increasing confrontation with this problem. The above mentioned case, a patient working with insulating materials on industrial heating systems, impressevely demonstrates the transformation of chronic laryngitis into a carcinoma in the course of years, brought about by industrial influences and thus proving the exogenous origin of this genesis. Dust as well as strong effects of heat under conditions of variable atmospheric humidily are concerned to be principal damaging factors.

Asbestos↗