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Biomedical subjects

G B Grassi

Publications and source records attributed to G B Grassi.

14 recordsLinked to original sources

Traumatic ventral hernia: report of a case, with special reference to surgical treatment.

A traumatic abdominal wall hernia is an unusual injury that may follow various types of blunt trauma. Differing patterns of muscular and fascial disruption can occur due to the different types of force involved as well as the tensile properties of the various areas in the abdominal wall. The anatomical defects which thus occur, therefore vary from small tears to large disruptions. A surgical repair is not always straightforward, and therefore close attention must be paid to such factors as the size and site of the defect, any associated intra-abdominal injuries, and the timing of repair, in order to achieve the best surgical repair. We consider the role of a computed tomography scan in the diagnosis of the muscular defects and associated injuries to be very important. Mesh repair offers an advantage in preventing recurrence in the presence of large defects, but strict criteria in their use must be followed, as the presence of hollow viscus injuries is an absolute contraindication to the use of mesh.

Accidents, Traffic↗

Giuseppe Grassi.

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Digestive System Surgical Procedures↗

[Infections caused by central venous catheter used in surgery].

The central venous catheters, now usually adopted in surgical patients, present some potential septic risks, and the longer the catheter is in place, the more dangerous it is. The authors report their experience on 130 central venous catheters, out of which 96 were used for TPN administration and 34 for monitoring purposes. The catheters were introduced through subclavian, internal jugular or basilic veins, in accordance with a standardized technique. The observed infection percentage, caused by the catheters, was 7.7%; the infection was easily controlled by the catheter removal and a proper antibiotic therapy. The only death, surely due to sepsis, was caused by Candida fungus in an immunosuppressed female patient. Therefore the authors stress the importance to prevent septic complications in order to avoid fatal ones.

Bacterial Infections↗

[Comparison of 3 different approaches to central veins in total parenteral nutrition].

The authors report their experience related to a series of 96 consecutive central venous catheters location through subclavian, right internal jugular, basilic and cephalic veins for TPN administration. Because of the specific complications reported, they are in favour of the trans-basilic peripheral approach for a short term TPN; the internal jugular or the subclavian way are indicated for long term ones. In addition, they stress the importance to limit the use of multilumen catheters just when absolutely necessary, due to the increased infection percentage.

Catheterization, Central Venous↗

[Reoperations in surgical oncology: recurrence of colon carcinoma after surgery].

Colon cancer is the second leading cause of death for cancer disease, after lung cancer, with nearly 18,000 deaths per year in Italy. In spite of the progress that have taken place over the past 30 years, little improvement has been gained in this dismal outcome, and the 5-year survival remains around 50%. Over one half of the patients will suffer from recurrence after a potentially curative resection. A major challenge lies in better detection of recurrences in order to diagnose those patients still amenable to curative resection. Locoregional recurrence is of particular interest and its frequency, diagnostic limitations and surgical treatment are herein discussed.

Biomarkers, Tumor↗