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Biomedical subjects

G Böttger

Publications and source records attributed to G Böttger.

At least 19 recordsLinked to original sources
PubMed1983

[Loss of neurons in the granular layer of the cerebellum in epilepsy].

Morphometric examination of the neurons in the cerebellar granular layer in epilepsy showed a significant mean decrease in their number. There is no correlation between this reduction and the duration of epilepsy or frequency of seizures, respectively. The pattern of lesions reach from slight patchy cell loss to severe diffuse reduction of neurons. The diameters of the granular neuronal nuclei showed a great variability. There is no correlation between age and the distribution of these diameters.

Adolescent↗
PubMed1981

[Liver rupture after prolonged use of contraceptive].

Since several years benign liver tumours have been observed as complication of a long-term intake of hormonal contraceptives. Apart from a clinical unconspicuousness uncharacteristic complaints of the epigastrium up to the picture of the acute abdomen due to rupture of the tumour rich in vessels may be appear. A preoperative diagnosis is only rarely successful, and only the laparotomy brings the final diagnostic clarification.

Adult↗
PubMed1980

[Benign hepatomata while taking oral contraceptives (author's transl)].

In recent years an increase in benign hepatomata during administration of oral contraceptives has been reported many times. A case is reported here of a 38-year-old woman who took such contraceptives for 8 years. The cardinal symptom was a tumor in the right upper quadrant of the abdomen. Laparotomy revealed several nodules in both lobes of the liver which could be almost completely removed by a wedge-shaped incision. Histologically a multicentric, focal nodular hyperplasia was present. Follow-up examinations after 24 months show no enlargement of the remaining tumor residues.

Adenoma↗
PubMed1980

[Effects of striatum stimulation and micro-iontophoretically applied dopamine and acetylcholine on the neuronal activity of the globus pallidus].

Alert, myorelaxed rats were used to study the influence of electrical stimulation of the stiatum and micro-iontophoretic application of dopamine and acetylcholine upon the discharge activity of neurons of the Globus pallidus. Out of 55 pallidal neurons, 25 responded to striatum stimulation with an initial inhibition and subsequent irritation, and 21 with an irritation-inhibition sequence. 40% of the neurons were dopamine-sensitive (23% irritation, 77% inhibition) and 38% choline-sensitive (63% inhibition, 37% irritation). 25% of the dopamine-sensitive neurons were at the same time choline-sensitive. There was no direct relation demonstrable between the effects of striatum stimulation and micro-iontophoretic application of acetylcholine or dopamine.

Acetylcholine↗
PubMed1977

[Therapy with synthetic ACTH].

With the development of the fully-synthetic preparation (tetracosactide) the therapy with ACTH has again obtained importance. The application in internal medicine above all takes place in rheumatoid arthritis and in bronchial asthma. Advantages and disadvantages are described and the possibility of withdrawal of cortisone is especially emphasized.

Adrenal Insufficiency↗
PubMed1975

[Total substitution of the esophagus after resection or as a temporary measure (author's transl)].

In recent years, communications have been made repeatedly on methods for substitution of the esophagus after total extirpation or as a temporary measure. However, under the impression of disappointments and resignation, the statistical material has remained small and so far it has not been possible to develop a skilled standard procedure. On the other hand, a partial substitution of the lower third of the esophagus by stomach has become a much-practised and usually successful surgical procedure. Total resection of the esophagus with surgical transposition is a big intervention, especially when perfomred as a single operation. But it is our opinion that when the patient's condition is satisfactory in respect of the indication for operation, one should certainly be critical but on the whole less restrained.

Age Factors↗
PubMed1975

[A method for the objective determination of tremors in the rat].

Two methods for determining tremors in the rat, acceleration pick-up and electromyogram, including electronic evaluation by impluse rate and frequency are described technically, and the results obtained with either method are compared. Both methods allow quantitative analysis of the drug induced (arecoline) tremor. Electromyographically, the tremor effect can be recorded already after lower doses compared with the electro-mechanical method. Besides, the EMG can be employed on immobilized animals.

Animals↗