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Biomedical subjects

G Barbero

Publications and source records attributed to G Barbero.

At least 55 records · Page 3Linked to original sources

Effects of acute viral respiratory tract infections in patients with cystic fibrosis.

To determine the effects of acute viral respiratory infections (ARI) in cystic fibrosis (CF) we studied all episodes of ARI in ten patients over a 2 year period. A daily diary card was kept on which they recorded all illnesses, including specific upper and lower respiratory symptoms, antibiotic use, and daily peak flow measurements. Recording of concurrent similar illnesses in other household members aided in confirming the onset of ARI, as did a home viral culturing technique and serial serum antibody levels against specific viral types. A total of 80% of the 35 recorded onsets of ARI (1.75/yr/subject) were confirmed by one or more of these methods. Five subjects with moderate to severe pulmonary function scores at the outset of the study had significantly greater decreases in PEFR during ARI episodes (42.4%) than those with milder disease (15.4%), and it took them significantly longer to recover to their baseline measurements (22 days vs. 15 days respectively). The majority of hospital admissions for pulmonary exacerbations were preceded by viral infections (7/8).

Acute Disease↗

[What role does the immune system play in the condition of a double form of atopy? Note I. Considerations on the behavior of the lymphocyte population and the immunoglobulins in children with atopic dermatitis in whom asthma develops].

Certain humoral and cellular immunological parameters were assessed in patients with either pure atopic dermatitis or dermatitis combined with asthma in order to discover if there were any significant differences between the two clinical forms. The study was conducted on 15 children of both sexes who were investigated for a familial history of atopy, serum immunoglobulins including the IgE group and certain lymphocyte populations. The data reveal that apart from the immunoglobulins, the other immunological parameters perform no differently in pure dermatitis than in dermatitis and asthma. It is therefore deduced that the immunological damage might be caused by the basic eczema.

Asthma↗

Depressive symptoms in children with recurrent abdominal pain and in their families.

Our purpose was to evaluate depression in children with recurrent abdominal pain and in their families. A self-report measure, the Children's Depression Inventory, and a psychiatric structured interview, the Child Assessment Schedule, were administered to 25 children with recurrent abdominal pain (RAP) as well as to 67 behaviorally disordered (BD) and 42 healthy children. Parents of all three groups completed the Beck Depression Inventory. On both measures, scores for RAP children were not significantly different from those of healthy children and were significantly lower than those of BD children. In contrast, the mothers of both the RAP group and the BD group had significantly higher depression scores than the mothers of healthy children. There were no group differences for fathers. The data suggest that although depression is not prevalent in children with RAP, depressive characteristics in the family may play a role in the origin of their abdominal pain.

Abdomen↗