Multifractality and multiscaling in collision cascades.
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Biomedical subjects
Publications and source records attributed to G Bardos.
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This study examines the role of different types of small intestinal distention of affective behavior. "Isovolemic" and volumetric distention were hypothesized to have different effects in rats. Both stimuli decreased fluid consumption in a free drinking situation equally. Behavioral correlates, however, were clearly different. Changes of the gut volume were accompanied by behavioral elements characteristic to aversivity while such changes were not observed when the distention was isovolemic. These results indicate that the cessation of intake, i.e., satiety, is not the consequence of the interference of concurrent aversive behavior. In contrast with these findings, isovolemic distention proved to be mildly unpleasant when tested by the taste-aversion method, although the effect was clearly distinct from that of volume changes. The results suggest that not avrsivity but discomfort may be a steady, inherent concomitant factor of physiological mechanoceptive gut stimuli.
Mannitol, a non-absorbent compound may suppress free drinking in rats. It was suggested that the osmotic accumulation of water in the intestine produced a satiety signal by distending the wall of the gut, which resulted in the reduction of intake. However, we never obtained this suppression during the first exposure to mannitol in water deprived rats, while subsequent administration of this compound significantly reduced the amount of the consumed fluid. Moreover, mannitol preloaded intragastrically increased and not decreased fluid intake. Results show that in water-deprived rats the accumulation of the fluid in the intestine did not result in satiety. The subsequent reduction of the fluid intake might be associated with the development of a taste aversion in the rats.