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Biomedical subjects

G Beets

Publications and source records attributed to G Beets.

4 recordsLinked to original sources

Clinical value of whole-body positron emission tomography with [18F]fluorodeoxyglucose in recurrent colorectal cancer.

To assess the clinical value of whole-body positron emission tomography (PET) with [18F]fluorodeoxyglucose (FDG) in recurrent colorectal cancer, 35 patients were studied: 15 had resectable liver metastases, one a resectable lung metastasis, eight resectable pelvic recurrence, eight a presacral mass with equivocal findings on imaging, and three increasing serum levels of carcinoembryonic antigen (CEA) without clinical or radiological signs of recurrent disease. PET affected management decisions in seven of 16 patients with metastatic disease. In one of eight patients with pelvic recurrence demonstrated by computed tomography (CT), PET detected unknown pulmonary metastases. In five of eight presacral masses with equivocal CT findings, PET was correct and unexpected distant metastases were detected in one of these patients. In two of three patients with increasing CEA levels and normal pelvic CT findings, pelvic recurrence was identified. Overall, whole-body PET affected management in 14 patients. PET is a valuable tool for staging local recurrence and metastatic disease.

Aged↗

Carotid artery surgery in the presence of an occlusion of the contralateral carotid artery: perioperative risk analysis and follow-up.

A retrospective study of 129 carotid artery reconstructions with an occlusion of the contralateral internal carotid artery (group CO) is presented. A control group comprised 489 patients with a stenosis of < 50% at the contralateral side (group CN). Both groups had the same mean age. There were fewer women in group CO (14% versus 31%, P < 0.0001), and more patients had a history of coronary heart disease (57% versus 44%, P < 0.05). In addition more patients of group CO had suffered a stroke (36% versus 27%, P < 0.05). A temporary shunt was used selectively and more frequently in group CO (87% versus 31%, P < 0.001). Major postoperative complications occurred with equal frequency in both groups: all strokes plus non-cerebral mortality (total combined morbidity and mortality): 4.65% versus 5.5%. The late incidence of stroke was the same in both groups: 8% in CO and 7% in CN at 5 years. The authors conclude that, under the described circumstances and with the appropriate surgical technique, the presence of an occlusion of the contralateral internal carotid artery does not imply an increase in major postoperative complications nor a higher stroke rate during follow-up.

Aged↗

Pulmonary function tests after different techniques for coronary artery bypass surgery. Saphenous vein versus single versus double internal mammary artery grafts.

Pulmonary function tests were measured in 33 male patients undergoing elective coronary artery bypass surgery. Three modes of surgical technique were used: Bilateral internal mammary artery graft (BIMA), single internal mammary artery graft (SIMA) and saphenous vein grafts (VS). Following parameters were recorded: patient's age, length, body weight, preoperative forced vital capacity (FVC) and forced expiratory volume at one second (FEV 1), preoperative end-diastolic pressure and function of the left ventricle, smoking habitus, the fact that the pleural cavity was entered, duration of the cardiopulmonary bypass period, perioperative fluid balance and postoperative FVC and FEV 1 on the first eight postoperative days. In the BIMA group two pleural cavities, the SIMA group one pleural sac and the VS group none of the pleural cavities was entered. The BIMA group was younger (50.1 +/- 7.6 versus 57.7 +/- 7.28 and 60.1 +/- 6.9 years (p less than 0.05)) than the SIMA and VS group. Postoperative external blood loss was lower in the VS group compared to the SIMA and BIMA groups (839 +/- 255 ml versus 1346 +/- 654 ml and 1259 +/- 396 ml (p less than 0.05)). The FVC shows a dramatic decrease especially on the second postoperative day and was most markedly diminished in the BIMA and SIMA compared to VS (31% +/- 9% and 35% +/- 8% versus 45% +/- 10% of preoperative values (p less than 0.05)).(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Arterial embolectomy. A long-term perspective.

One hundred and thirteen elderly patients (median age 77 years, range 37-99) were followed up for 2-10.5 years after embolectomy in order to assess the late outcome. There were two groups of patients: those who had suffered an embolism (84) and those who in retrospect had thrombosis in situ (29). Thirty three of the embolus group (39%) died within 30 days of surgery, and factors associated with mortality (p less than 0.05) were age greater than 80 years, and failure to save the limb (17%). In the thrombosis group limb loss was more common (76%) and these patients also had a higher mortality (55%). Mean long term survival in the embolus group was 35 months (range 1-108 months) with a high mortality rate in the first 6 months after embolectomy and improved survival after this. There were no significant differences in mortality or cardiovascular events between the 27 patients on long term warfarin and the 19 patients not anticoagulated. Mortality after embolectomy is high but there remains a group of long term survivors. The value of oral anticoagulation for these patients remains unresolved.

Adult↗