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Biomedical subjects

G Benoit

Publications and source records attributed to G Benoit.

At least 37 records · Page 2Linked to original sources
PubMed1990

Transplant renal artery stenosis: experience and comparative results between surgery and angioplasty.

One hundred thirty-eight patients with transplant renal artery stenosis (TRAS) were identified among 1200 patients undergoing renal transplantation in our university hospital. Severe systemic hypertension was the main symptom leading to a diagnosis of TRAS. Only 88 TRAS patients were given interventional treatment consisting of percutaneous angioplasty (PTA; n = 49) or surgical repair (SR; n = 39). The immediate success rate was 92.1% for SR and 69% for PTA. The long-term success rate was 81.5% for SR and 40.8% for PTA, with a follow-up period of 56.7 +/- 22.4 months (SR group) and 32 +/- 28.1 months (PTA group). PTA morbidity reached 28%, compared to 7.6% in the SR group. In spite of these results, we still favor PTA as a first line interventional treatment when TRAS is recent, linear, and distal and primary SR in cases of kinking and proximal TRAS.

Adolescent↗
PubMed1990

[Autosomal dominant polycystic kidney in adults].

The authors present a general review of autosomal dominant transmission of polycystic kidneys. It represents 10% of all causes for haemodialysis. Its penetrance is close to 100%. The dominant aetiology at the present time is obstruction due to hyperplasia of the tubular epithelium which induces cystic dilatation which extends to involve all of the nephron. The cysts are cortical and medullary. The diagnosis is based on an association of enlarged kidney and a family history. The commonest associated abnormalities are hepatic cysts in 60% of cases, cerebral aneurysms in 10 to 20% of cases and colonic diverticulosis in 80% of cases. At the stage of renal failure, patients must be treated for hypertension and deterioration in nephron function must be prevented by a low protein diet. When the patient reaches the stage of renal failure and must be dialysed, he must be rapidly enrolled in a transplantation programme as the actuarial graft survival is more than 80% at 1 year and more than 70% at 5 years.

Adult↗
PubMed1990

[Autosomal dominant polycystic kidney in adults and transplantation].

Seventy-six patients with polycystic kidneys were followed in the Bicêtre renal transplantation unit. Fifty four were transplanted. Fifty two nephrectomies were performed in these patients essentially because of the size of the kidney and for renal infections. Fifty four patients were transplanted at a mean of 44 years. The actuarial survival of the patients at one year and at three years was 92% and 88% and the actuarial survival of the grafts at one year and at five years was 87% and 71%. These results are comparable to those obtained in other patients transplanted in the unit. Pre-transplantation nephrectomy and the patient's age do not aggravate the prognosis. Nephrectomy may be justified in these patients when they must be transplanted as transplantation currently gives very good results.

Adult↗
PubMed1990

[Harvesting multiple organs].

The development of organ transplants is limited by the shortage of organs. The improvement of this situation depends on two factors: increased awareness by the general public that refraining from refusing the removal of organs from the body of a patient with brain death is the most modern form of solidarity; and increased awareness by the medical profession that removal of organs should be proposed for every patient with brain death and that adequate resuscitative techniques should be used to preserve the organs in these patients. When the decision to harvest organs is taken, the transplant specialists must decide whether an organ should be used or not. Advances have been made in preservation techniques but are still insufficient to allow a reduction in immunosuppression. The UW solution is a major advance for liver, kidney and pancreas transplants. During harvesting, the separation of the vascular pedicles requires a good knowledge of surgical anatomy. Furthermore, the needs of the other surgical groups should be taken into account and concessions made to allow the harvesting of the greatest possible number of organs and consequently the treatment of the largest number of patients awaiting organs.

Brain Death↗
PubMed1990

[Computer-assisted prostate reconstruction].

The authors report a technique of computer assisted three-dimensional reconstruction using the information obtained from serial sections collected on a digitalizing table. This reconstruction was performed with a popular personal computer: Macintosh. This technique was applied to the reconstruction of the animal prostate.

Animals↗
PubMed1990

[Treatment of PT1 tumors of the bladder using transurethral resection and intravesical immunotherapy].

Twenty-six patients with a PT1 urothelial bladder tumour were treated by transurethral resection and endovesical BCG. The authors compared previously untreated patients with patients with a history of bladder tumour present for an average of 4.6 years. The results of this study show that 72% of bladders in the first group were preserved compared with 53% in the second group. 45% of patients in whom the tumour invaded the superficial lamina propria developed a recurrence compared with 100% of tumours with invasion of the deep lamina propria. 25% of patients who developed a recurrence died in the course of this study.

Administration, Intravesical↗
PubMed1990

[A double balloon catheter for the procurement of abdominal organs].

When harvesting kidneys, a double balloon catheter can be inserted either at the bedside if cardiac arrest occurs or in the operating room. This catheter reduces the time required for dissection of the aorta and decreases the amount of fluid needed to cool the organs.

Catheterization↗