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Biomedical subjects

G Benz-Bohm

Publications and source records attributed to G Benz-Bohm.

At least 37 records · Page 2Linked to original sources
PubMed1990

MRI of the knee region in leukemic children. Part II. Follow up: responder, non-responder, relapse.

Part II demonstrates the results of MRI follow up studies of 23 children with leukemia. Differentiation between leukemic cells and normal hematopoiesis by MRI is impossible. The state of disease can only be determined together with bone marrow biopsy. Clinical remission precedes the normalization of bone marrow signal by weeks. In non-responders, however, cytological findings and MRI findings seem to correlate at the same time. During therapy, areas of osteonecrosis may develop. They do not necessarily contradict continuing complete remission. But this does not affect the prognosis and complete remission is still a possibility. Diagnosis of relapse by MRI is only possible in correlation with studies during the different states of disease especially at clinical remission.

Adolescent↗
PubMed1990

[Nuclear magnetic resonance tomographic diagnosis of brain tumors in children and adolescents. A comparison with computed tomography].

Thirty-one pediatric patients with brain tumors--25 primarily diagnosed, 6 recurrences--underwent MR and CT examinations before and after application of contrast media. Tumor detection, delineation of the tumor extent and definition of the tumor type were compared. Gd-DTPA-enhanced MR was superior in delineating the extent of primarily diagnosed tumors, which showed enhancement (n = 22). The tumor detection (1/6) and the identification of the tumor margins (5/6) were improved by Gd-DTPA in the 6 recurrences. Tumors without enhancement (n = 3) were judged by T2-weighted images better than by CT. The results suggest that Gd-DTPA is indicated for the evaluation of brain tumors in pediatric patients as well, especially since it offers advantages distinguishing between tumor types. Only the detection of tumor calcifications, which is rarely specific, is not possible by MR.

Adolescent↗
PubMed1990

[Bone marrow metastases of neuroblastoma: MRT in comparison with bone marrow cytology and mIBG scintigraphy].

Thirteen MRT investigations of the knee region of nine children with neuroblastoma stage IV/III were performed in order to demonstrate bone-marrow metastases. The MRT-findings were correlated with bone-marrow cytology, immunofluorescence, and mIBG-scintigraphy. MRT showed a high sensitivity in demonstrating bone-marrow abnormalities, although bone-marrow aspiration and mIBG-scintigraphy will still be needed to make a specific diagnosis. On the other hand, signs of bone-marrow involvement in MRT investigations without positive findings in bone-marrow cytology and mIBG-scintigraphy may be the first evidence of bone-marrow metastases.

3-Iodobenzylguanidine↗
PubMed1990

[Multiple aneurysms of unknown etiology in childhood--complications and diagnostic possibilities].

A 6.5-year old boy with already known multiple aneurysms of all major arteries presented with acute abdominal pain. As demonstrated by ultrasound a big aneurysm of the left renal artery thrombosed in the course of three days. As a result, the left kidney developed severe ischaemia. Although computed tomography and scintigraphy were applied, a plan for a definitive therapeutic procedure could be established only by arterial angiography. Both Ehlers-Danlos' syndrome and Kawasaki's syndrome were excluded. There were no facts suggesting an infective aetiology. Four other cases with multiple aneurysms of unknown aetiology in childhood have so far been described in literature.

Aneurysm↗
PubMed1989

Mycoplasmal pneumonias in childhood. Roentgen features, differential diagnosis and review of literature.

The chest radiographs of 23 children, aged between 4.2 to 15.4 years with serologically proven mycoplasmal pneumonia were reviewed and correlated with the findings in literature. Three different patterns of infiltration were seen in equal frequency: 1) peribronchial and perivascular interstitial infiltrates, 2) patchy consolidations and 3) homogeneous acinar consolidations like groundglass. The lower fields of the lungs were mostly affected. Pattern 1 was always observed bilaterally. Enlargement of the hilar glands was a common finding. Pleural effusion was rare. Numerous differential diagnoses, especially viral pneumonias, feature the heterogeneity of the infiltration patterns. As no pattern is pathognomonic for mycoplasmal pneumonia clinical symptoms and signs, the epidemiological situation and laboratory data may confirm the diagnosis.

Adolescent↗
PubMed1989

[Pleuromediastinal lines in infants, children and adolescents--a contribution to knowledge of the normal x-ray anatomy of the mediastinal borders].

The roentgen anatomy and incidence of the most frequent pleuromediastinal lines and stripes (PML) on the sagittal chest film during the first 18 years of life are analysed. It is only on involution of the thymus that the PMLs of the superior mediastinum (anterior contact line, right paratracheal stripe, arteriovenous left subclavian lines, "aortic nipple", supra-azygous posterior pleural line) are modelled out. Between the 2nd and 6th year of life they attain their normal appearance typical for adult life. The PMLs of the posterior inferior mediastinum (paraspinal lines, infra-azygous posterior pleural line) are most frequently observed between the 6th and 18th year of life. Absence of a PML as a single finding is not pathological. Displacement, widening or opacification of a PML, specially if they affect only a segment of the PML, may be indicators of a pathological process within the mediastinum itself or in the adjacent lung or pleura.

Adolescent↗
PubMed1989

[Nephrocalcinosis in childhood. Sonographic findings and differential diagnosis].

Ultrasonography is the method of choice for the detection of medullary or cortical nephrocalcinosis in infancy and childhood. Compared with abdominal radiographs and computed tomography even smallest calcifications are detected more accurately. Using furosemide, ACTH, steroids or high doses of vitamin D, early forms of medullary nephrocalcinosis associated with a faint hyperechogenic rim at the margins of the renal pyramids can be diagnosed by ultrasound. Idiopathic hypercalciuria, Bartter's syndrome and renal tubular acidosis cause medullary nephrocalcinosis, whereas cortical nephrocalcinosis is the result of renal vein thrombosis; primary hyperoxaluria is associated with cortico-medullary calcifications. Due to the localisation of the nephrocalcinosis and the age distribution of the diseases, sonography merely enables us to narrow down differential diagnosis.

Aging↗
PubMed1988

Di-(2-ethylhexyl)-phthalate as plasticizer in PVC respiratory tubing systems: indications of hazardous effects on pulmonary function in mechanically ventilated, preterm infants.

Several PVC medical devices contain the plasticizer Di-(2-ethylhexyl)-phthalate (DEHP) in high concentration. Taken systematically DEHP only has minor toxic effects in the human organism. In three preterm infants artificially ventilated with PVC respiratory tubes unusual lung disorders resembling those observed in hyaline membrane disease, verified both clinically and radiologically, were observed during the fourth week of life. It was assumed that these lung disorders were causally related to the exposure to high doses of DEHP, which was released from the walls of the respiratory tubes. DEHP was found in the lung tissue of one patient who died of pneumothorax soon after birth after being artificially ventilated. It is strongly recommended that for disposable PVC respiratory devices the plasticizer DEHP should be used with more restrictions.

Diethylhexyl Phthalate↗
PubMed1987

[Is hip sonography meaningful as a screening method?].

The results of screening 162 non-selected neonates by sonography of the hips indicate that this is not a desirable screening method. Sonography is, however, indicted in neonatal groups which are considered to be at risk.

Female↗
PubMed1987

[Is hip sonography in premature infants necessary as a screening procedure?].

Screening sonography of the hip in 132 premature infants indicates that prematurity is not a risk for congenital dysplasia/dislocation of the hip. However, for reasons explained in the text, screening should be carried out before discharge from hospital. Follow-up examinations are necessary only for infants with known risk factors for dysplasia/dislocation of the hip.

Female↗
PubMed1986

[Aortic dissection in childhood. Occurrence and diagnostic procedure].

Aortic dissections of the aorta thoracalis are rare in childhood, and mostly cause a life-threatening situation in which an immediate diagnosis is the key for survival. Main causes are an aortic vitium or a traumatic disruption. The conclusive diagnosis can only be obtained by a chest-X-ray, the two-dimensional echocardiography and the dynamic computed tomography scanning of the thorax. It must be taken into account, that patients with a polytrauma could possibly suffer from a traumatic aortic dissection, which sometimes can only be diagnosed at a later date.

Adolescent↗
PubMed1984

Wegener's granulomatosis in childhood. Review of the literature and case report.

Wegener's granulomatosis (WG) is a rare disease in pediatric patients. The case of a 14-year-old girl with generalized WG is described and the pediatric literature reviewed. Thirty additional cases of WG in childhood have been traced in previous studies. Diagnostic problems are discussed in the context of clinical, radiological and biopsy findings.

Adolescent↗
PubMed1984

[Neurofibromatosis in childhood. Computed tomographic findings in the skull and neck areas].

The value of CT was investigated in sixteen children and adolescents with neurofibromatosis affecting the skull and neck. Its advantage is the simultaneous demonstration of bone and soft tissue changes, which frequently occur together in this condition. Demonstration of the extent of the neurofibromatous soft tissue changes is of crucial importance to the surgeon when planning treatment. Serial observations provide information on progress of the disease and helps in the decision of the optimal time for surgery. The differential diagnosis is discussed.

Adolescent↗