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Biomedical subjects

G Benz

Publications and source records attributed to G Benz.

At least 55 records · Page 3Linked to original sources

[Problem of fracture of the radius head in the child].

Guidelines for the choice of conservative or operative treatment of fractures of the proximal radius are derived from a study comprising 21 children. Postoperative complications and long-term failures are specifically stressed. True intraarticular fractures of the radial head are rarely observed in children. Major problems arise in the treatment of comminuted fractures of the radial head associated with dislocation of the elbow, since these show the worst prognosis. Displaced marginal fractures below 3 mm are suited for early functional treatment using conservative procedures. 18 patients suffered a fracture of the radial neck type III and IV (Judet). Despite low failure rates of the operative therapy, we have recently been refraining from the operation.

Adolescent↗

[The importance of scintimetry in the differential diagnosis of roentgenological areas of increased "translucence" in the skeleton of children (author's transl)].

A random selection of lesions representing osteolytic bone processes was evaluated with the "region-of-interest" technique in order to determine whether scintimetry can be helpful in the differential diagnosis of such processes in children. Bone tumours with structural densification, as well as osteomyelitides, were reviewed for comparative purposes. It was found that scintigraphy of the skeleton, while supplying additional and clinically quite interesting information, does not make any substantial contribution to the differential diagnostic clarification of roentgenological translucence in the skeleton of children.

Bone Resorption↗

Renal bone disorders in children: therapy with vitamin D3 or 1,25-dihydroxycholecalciferol.

Twelve children with chronic renal failure (CRF) and sixteen children receiving regular dialysis therapy (RDT) were treated with between 10,000 and 50,000 IU of vitamin D daily. This was associated with an increase in serum calcium levels and reduction in PTH levels. In the children with CRF, secondary hyperparathyroidism was improved with treatment but its development was not completely prevented nor was healing complete. In the patients receiving RDT, treatment with vitamin D improved the changes associated with secondary hyperparathyroidism in 50% of cases but these features sometimes reappeared despite continuing treatment. Hypercalcaemia or metastatic calcification was not seen. Subsequently, 1,25(OH)2D3 was administered to 14 children receiving RDT. This was associated with the return of serum calcium levels to normal, inhibition of PTH synthesis and an improvement in intestinal calcium absorption. Fibro-osteoclasia was cured and there was improvement in actual bone resorption. There was also improvement in osteoidosis in those children who showed disturbances of mineralisation. Calcification in the limbus area of the eyes may occur and hypercalcaemia was seen commonly. Treatment with 1,25(OH)2D3 should only be offered to children with severe renal bone disease. Neither vitamin D3 nor 1,25(OH)2D3 can guarantee complete recovery of osteodystrophy and of growth arrest in uraemic children.

Adolescent↗

[Plain film findings in the skull in neurofibromatosis (author's transl)].

The radiologically demonstrable changes in the skull, which occur in neurofibromatosis, are described. The mesodermal dysplastic changes in the sphenoid and the facial skeleton are diagnostic. Changes secondary to blastomatous processes are not always a consequence of the presence of a tumour; they may result from developmental abnormalities or dural protrusion. In addition one may encounter a series of changes which are not in themselves diagnostic. Problems in the diagnoses and the differential diagnosis are discussed.

Child↗

Pycnodysostosis with Heterozygous beta-thalassemia.

A 6-year follow-up of a Greek girl with pycnodysostosis associated with heterozygous beta-thalassemia is reported. Active rickets in infancy was superimposed on pycnodysostosis. In the family the autosomal recessive disease, pycnodysostosis, appeared in two of three siblings in combination with the autosomal dominant disease, thalassemia minor.

Child↗

Upper calyx reno-vascular obstruction in children: Fraley's syndrome.

Intrarenal vascular obstruction of the upper calyceal infundibulum has been distinguished by Fraley as an entity separate from an asymptomatic vascular impression. Clinically, this form of intrarenal vascular obstruction presents as nephralgia or hematuria. This infundibular obstruction is caused by normal renal vessels, usually the upper segmental artery: radiologically, the vessels produce a constant well-defined filling defect in the infundibulum at IVP, and, the upper calyx group is distended and shows delay in emptying. We found this condition in 14 children from 1968-1975. Control studies showed no progression in the radiological findings, even over a long period. In one of our cases angiography was indicated to exclude tumour or cyst; in another case, surgery was necessary. Complications are urinary tract infection or stone formation. Therefore, children with Fraley's syndrome require regular clinical examination.

Child↗

Segmental renal hypoplasia in childhood.

Radiological findings of segmental renal hypoplasia are reported, based on the observation of 6 children aged between 8 and 14. The leading clinical symptom is arterial hypertension. Urinary tract infection and proteinuria are additional common findings. Cases with bilateral disease often have renal failure. The intravenous urogram shows unilateral or bilateral small kidneys with segmental renal scarring and transverse lobulation. In the pathological areas the calyces are ectatic or clubbed and their infundibulum is elongated. Vesico-ureteral reflux is frequent. In angiography the lobulated segments appear hypovascular. Diagnosis was verified by histological examination.

Adolescent↗

Action of Bacillus thuringiensis preparation against larch bud moth, Zeiraphera diniana (Gn.), enhanced by beta-exotoxin and DDT.

Addition of either DDT or the supernatant of a centrifuged liquid culture of Bacillus thuringiensis, serotype H1, containing beta-exotoxin, enhanced the action of the bacterial preparation Thuricide 90 T against larvae of the larch pest Zeiraphera diniana, increasing mortality from 53% to more than 80%. Since DDT alone produced 57% mortality, its combined action corresponds to independent action. The preparation of beta-exotoxin, on the other hand, had only little effect alone but synergized the action of the bacterial preparation considerably.

Animals↗

[Hemobilia. (Apropos of 5 cases)].

Hemobilia or hemorrhage through the biliary tract is increasing in frequency. With spreading knowledge of the syndrome, the diagnosis is now rarely missed. There is also a real increase due to traffic accidents which often cause liver injuries. The typical triade with digestive hemorrhage, biliary colic and jaundice should always arouse suspicion of hemobilia. Hepatic angiography is the best and most accurate diagnostic method. Accidental or operative trauma constitute the major cause of macroscopic hemobilia where as microscopic hemobilia is a very frequent symptom in gallstone-disease. In this report five cases of different ethiology are described. Three were caused by abdominal trauma. The fourth case illustrates the risk of hemobilia from instrumental exploration of the common duct. Even when this is done carefully it might cause a hemorrhage with formation of obstructing clots. In the last patient there was severe hemobilia due to errosion of the cystic artery by a gallstone, penetrating into the duodenum. The treatment given in the five cases are examples of different methods which may be used, according to the nature of the lesion. In the three cases of traumatic hemobilia one healed spontaneously under angiographic control, one was cured by local hemostasis in the central liver rupture and the third had a successful hepatic resection. In the case with post-operative hemobilia, an obstructing clot had to be removed from the common duct. Simple cholecystectomy cured the patient with hemorrhage from the eroded cystic artery.

Aged↗

[Radiological diagnostic of retroperitoneal extrarenal tumors in childhood (author's transl)].

This reports about 54 children suffering from retroperitoneal tumors excluding renal tumors. Characteristic radiological findings of neuroblastomas, pheochromocytomas, suprarenal carcinomas, adenomas, and teratomas are discussed. The diagnosis is made by the following roentgenological investigations: intravenous urography via the V. cava as "Cavo-Urography" or infusion urography (including zonography), sonography and nuclear medicine studies. Arteriography, pneumoretroperitoneum and lymphography are indicated if the primary tumor is unknown, in order to reveal suspected metastases, to decide about operability and for controlling radiotherapy. Further radiological examinations are made depending on the type of the metastasis.

Adenoma↗