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Biomedical subjects

G Berggren

Publications and source records attributed to G Berggren.

14 recordsLinked to original sources

Dynamic neck strength training effect on pain and function.

This study examined whether neck resistance training could increase strength and reduce pain in workers with a high prevalence of neck disorders. Middle-aged women workers (n = 17) exercised twice weekly for 8 weeks. Each session (12min) consisted of three sets of 12 repetitions of resisted rotation, flexion, and extension muscles using hydraulic dampers. Resistance was set individually and progressively increased every second week. Angle-specific maximal isometric rotator, extensor, and flexor torque was measured before and after training. Torque during rotation, flexion and extension increased (p < .05) on average 35%, 27%, and 19%, respectively, after training. Perceived pain, assessed using a four-graded scale, was reduced (p < .05) after training. It is suggested that 12 minutes of specific neck strength training twice weekly for 8 weeks increases strength of rotator, extensor, and flexor muscles of the neck. Also all individuals who had pain reported reduced perceived neck pain after training.

Adult

Correlation between quantitative in vivo and in vitro responses in nickel-allergic patients.

Forty-three nickel-allergic patients (40 females and 3 males) participated in this study which was designed to elucidate the correlation between quantitative in vivo and in vitro responses. All were patch-tested with various concentrations of nickel-sulphate serial-diluted in water. The lowest concentration eliciting a cutaneous reaction (indicating the severity of the allergy) was recorded for each individual and compared with the in vitro lymphocyte response, using the lymphocyte transformation test. The best correlation coefficients obtained were 0.42 and 0.46, tested for linear and logarithmic correlation respectively. However, there were individuals who showed a weak cutaneous response and high lymphocyte reactivity. The converse situation was also found, however, indicating that other mechanisms than those mediated via lymphocytes may be of significance in the patch test response.

Adolescent

Preinvasive carcinoma of the cervix uteri and smoking.

The occurrence of smoking among 609 women with preinvasive cervical uterine cancer has been examined. Of these women, 66.3% were smokers. For 6 090 controls the figure was 41.9%. The difference is statistically significant (p less than 0.001). In all the age groups the proportion of smokers was greater among the women with cancer. These also started smoking at an earlier age, and the number of cigarettes smoked daily was greater than for the controls.

Adolescent

The influence of renal function on plasma levels and urinary excretion of acebutolol and its main N-acetyl metabolite.

The pharmacokinetics of acebutolol and its major N-acetyl metabolite diacetolol were determined following acute intravenous and chronic oral administration to 22 subjects with glomerular filtration rate (GFR) between 3 and 127 ml/min. Following chronic oral administration the mean terminal elimination half-life of unchanged acebutolol was about 10 hours independent of renal function, whereas the hall-life of the N-acetyl metabolite increased from 12.8 hr in subjects with normal renal function (GFR greater than 90 ml/min) to 24.0 hr in preuremic patients (GFR less than 10 ml/min). The mean area of the plasma level-time curve (AUC) of the metabolite was 14.2 mg 1-1 hr in patients with normal renal function and rose to a value of 81.4 mg 1-1 hr in preuremic patients. The mean AUC of the parent drug was not influenced by changes in renal function. The considerable accumulation of the acetyl metabolite, which has about the same beta blocking activity as the unchanged drug, necessitates dose reduction of acebutolol in the presence of different degrees of renal impairment (reduction by half of the normal daily dose in patients with GFR between 30 and 10 ml/min and by three quarters when GFR less than 10 ml/min). In subjects with normal renal function, the ratio between the AUC of the parent drug and that of its major N-acetyl metabolite was 3:1 after intravenous injection of the drug, while it was 1:2.5 following chronic oral administration, indicating a marked first pass metabolism of acebutolol.

Acebutolol

Acute water shortage and health problems in Haiti.

During a severe drought Port-au-Prince, Haiti, lost hydroelectric power for 10 weeks. This led to water shortages in areas of the city dependent on water supplied from electrically driven pumps. In a study of the impact of water restriction on disease, 400 families were randomly selected from two urban areas differentially affected by the water shortage. Disease in children was found to be related to quantity of water used, socioeconomic status, employment of head of household, and family size. The methods used in this study are recommended for the investigation of the relationship between water quantity and health.

Drinking

Physical work capacity of young men in Sweden.

Each year between 1961 and 1975 all male students in a secondary school were submaximally tested on several occasions on bicycle ergometers with regard to estimated maximal aerobic power. The school is situated in central Sweden (Falun). The students were between 16 and 20 years of age. Data from the tests in Falun and data compiled from other sources cannot confirm the hypothesis that young men of today have a lower maximal aerobic power than young men of the 1960s. The results indicate that Swedish boys aged 16 to 20 have, on average, a maximal aerobic power of about 45 ml O2 X (kg x min)-1. The standard deviation is about 8 ml O2.

Adolescent

Preventive and therapeutic benefits in relation to cost: performance over 10 years of Mothercraft Centers in Haiti.

Evaluation of the effectiveness of Mothercraft Centers operating in Haiti over the period 1964 to 1975 as a public health measure in private and public health services is reported. For the most part, the data are derived from centers operating routinely in the health services rather than from pilot demonstrations. Their impact in both therapy and prevention of severe malnutrition in preschool children is considered, and it is found that numerically the greater benefit is in prevention. At a total annual cost of $4034 a typical center accomplishes successful therapy and prevents relapse in 105 children. In addition, it provides protection against severe malnutrition to their 306 younger siblings. It is thus estimated that, considering only these 411 children demonstrably benefited from a year's operation, the cost of providing essentially lifetime protection from severe malnutrition is approximately $10 per child.

Body Weight