[Eulogy of Jean-Louis Parrot (1908-1991)].
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Biomedical subjects
Publications and source records attributed to G Blancher.
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We gather, under the expression of regulation, both Parliament Acts and general texts emanating from executive Authorities. The analysis must be made according to the source of noise. So we have successively examined noisy equipment, industrial, commercial and agricultural activities producing noise, noisy material, carriage, leisure activities, building and neighbourhood noises, and after all the protection of working people. We have also studied the organization of the fight against noise, since it depends on law. Finally, this regulation is already very rich, including both texts directly concerning the fight against noise and other texts belonging to wider regulations (protection of environment or protection of working people). On the whole it seems to be well adapted to its objective, the prevention, even if it may be completed. The main thing is a better application to matters concerning everyday life and striking opinion, such as neighbourhood and traffic noises. It will be surely evolutive, first by connection with related and wider regulations, and above all according to the progress of our scientific and technical knowledge. Thus it will be constantly adapted, if exactly applied, to the needs of prevention.
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Fifteen children with immunological thrombocytopenic purpura were treated by first intention with high dose intravenous gammaglobulins (Venoglobulins and Sandoglobulins). Nine children recovered after the first injection with platelet counts greater than 50,000/mm3 after 2 days' treatment, so countering the risk of haemorrhage. One child required a second course of treatment and was then cured. Three children had temporary rises in their platelet counts and then relapsed; two children did not react at all to the treatment. The most interesting feature of this new therapeutic approach is the possibility of preventing serious haemorrhagic complications in cases of severe thrombocytopaenia (less than 10,000/mm3) by inducing a rapid rise in the platelet count.
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In view to study the effects of thermal environment on the development and the thermogenic activity of interscapular brown adipose tissue (BAT), young rats born at 23 degrees C or 28 degrees C were sacrificed at 1, 3, 7, 11, 14 or 21 days after birth. The rate of increase in animal weight was quite the same at both temperatures up to the 14th day. The development of BAT and its contents in lipids, in water and in noradrenaline indicate that the energetic activity of the tissue is greatly stimulated in rats kept at 23 degrees C up to the 11th day. It is concluded that in rats bred in the habitual thermal conditions (23 degrees C), the occurrence of non shivering thermogenesis (NST) is important during the period of ten days after birth; in the following period NST could be progressively replaced by other thermoregulatory processes.
The weight and the lipid, water and norepinephrine contents of the interscapular brown adipose tissue from 1, 3, 7, 11, 14 and 21 day aged rats were measured. The animals were maintained at an ambiant temperature of 16 degrees, 23 degrees or 28 degrees C from birth. It is concluded that nonshivering thermogenesis is not necessary after 3 days of age in animals kept at 28 degrees C and after 11 days of age in the ones kept at 23 degrees C. However that thermogenesis persists for all the suckling period in those kept at 16 degrees C.
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