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Biomedical subjects

G Blanco

Publications and source records attributed to G Blanco.

At least 145 records · Page 8Linked to original sources

Neuroradiological correlates of frontally predominant intermittent rhythmic delta activity (FIRDA).

A correlative, retrospective review of 80 consecutive cases of EEG FIRDA was performed with regard to the neuroradiological findings: 62 of the 80 patients had had CAT scan evaluations. Of the 61 patients with structural pathology, 53 had CAT scans which were abnormal in 40 (76%); of the 19 patients with 'non-structural' (mostly metabolic) brain lesions, 10 had normal CAT scans. In the structural group with normal CAT scans, the presence of pathology was demonstrated by arteriography (5 cases), radionuclide cysternography (1 case), brain scan (1 case), or pathological examination. Patients with 'non-structural' FIRDA had a significantly higher probability of being in an altered state of consciousness and of having abnormal background activity in their EEG. Focal EEG abnormalities are more frequently associated with structural lesions and FIRDA. If FIRDA is present on the EEG, further neuroradiological studies should be considered, especially with other electroclinical information suggests a non-metabolic substrate.

Central Nervous System Diseases↗

Preserved arterial grafts in microvascular surgery.

The patency rates of arterial grafts preserved by immersion in 70% alcohol and arterial grafts preserved by ficin digestion and dialdehyde tanning were compared with the patency rate of fresh autogenous vein grafts in 5-mm defects in the femoral arteries of 50 rats. The overall patency rate for the fresh vein grafts was 90%. The patency rate at 2 weeks for the alcohol-preserved arterial grafts was 40%; the patency rate for the dialdehyde-tanned arterial grafts at 2 weeks was 30%. The difference between the rates for the fresh vein grafts and the alcohol-preserved and dialdehyde-tanned grafts was statistically significant (P less than 0.01 and P less than 0.001, respectively). At 2 months there was no statistically significant difference in the rates between the autogenous vein grafts and the preserved arterial grafts, probably because of recanalization of grafts that had occluded primarily. From the data, it is concluded that fresh autogenous vein grafts are still superior to preserved arterial grafts in microvascular surgery.

Animals↗

Acid alpha-naphthyl acetate esterase (ANAE) activity and DNA synthesis of lymph nodes cells in Hodgkin's disease.

Lymph node and peripheral blood lymphocytes in a case of Hodgkin's disease (mixed cellularity) were studied using May-Grünwald-Giemsa (MGG), acid naphthyl acetate esterase (ANAE), immunoperoxidase staining and lymphocyte surface markers, autoradiographic, and lymphocyte stimulation techniques. According to MGG staining and autoradiographic studies of lymph, node cells, small lymphocytes, intermediate lymphoid cells, and large mononuclear cells resembling in-vitro stimulated immunoblasts, Hodgkin's cells and Reed-Sternberg (RS) cells formed a morphologically continuous DNA synthetizing series. A large majority of small lymphocytes from a lymph node were ANAE positive, thus being T-lymphocytes, and formed rosetts around large mononuclear cells and RS cells. Most RS and large mononuclear cells had ANAE positive spots in the cytoplasm, thus resembling T-lymphocytes more than diffusely staining monocytes. These cells did not contain cytoplasmic immunoglobulin and were muramidase negative. Both lymph node and peripheral blood lymphocytes responded strongly to PHA. The role of T-lymphocytes in Hodgkin's disease and the origin of RS cells are are discussed on the basis of the findings.

Adult↗

A controlled surgical approach to annulo-aortic ectasia.

Annulo-aortic ectasia has attracted much surgical attention in the last 20 years. Replacement of the aortic valve and ascending aorta from the valve ring to just proximal to the innominate artery eliminates most, if not all, the pathologically involved tissue. Composite valve-Dacron tube grafting, plus elective saphenous vein grafts from the coronary orifices to the Dacron tube or distal aortic wall, provide a safe systematic approach to this entity. A review of surgical techniques and a description of a successful case employing this method are presented.

Adult↗

Dissection and rupture of the ascending aorta. Unusual complications of aortocoronary bypass surgery.

This is a report concerning two cases of unusual complications, dissection and rupture of the ascending aorta, secondary to saphenous vein bypass surgery. We recommend that evaluation of patients undergoing saphenous vein bypass surgery include careful image-intensifier fluoroscopic examination during coronary arteriography. If aneurysmal dilatation of the aorta or calcification is observed, ascending aortography should be performed to better evaluate the aorta, and surgeons should be alerted to use appropriate maneuvers and techniques to minimize the risk of complications in the aortic site of the vein anastomosis. Internal mammary coronary-artery bypass should be the procedure of choice in such conditions.

Aortic Aneurysm↗