PubMed Health⌕ Search

Biomedical subjects

G Blin

Publications and source records attributed to G Blin.

7 recordsLinked to original sources
PubMed2005

First-trimester ultrasound diagnosis in a recurrent case of Walker-Warburg syndrome.

We report on two siblings with Walker-Warburg syndrome (WWS) born to a consanguineous couple. In the index case, the second-trimester scan showed ventricular dilatation and we diagnosed WWS after observing retinal detachment at 26 weeks' gestation and lissencephaly by 32 weeks' gestation in addition to hypoplasia of the cerebellar vermis. The second case was first suspected at 12 weeks' gestation, when we observed a 2.8-mm nuchal translucency and an unusually large hindbrain vesicle. By 14 weeks' gestation, the lateral ventricles were clearly enlarged (12-13 mm), at 16 weeks' gestation the vitreous chamber appeared to be hyperechogenic, and by 17 weeks' gestation hydrocephalus was evident. The couple chose to continue the pregnancy, and during the third trimester lissencephaly, major hydrocephalus and polyhydramnios developed. Serial ultrasound examination should be offered to a family with a history of WWS and therefore a 1 in 4 risk of recurrence. In some cases, recurrence can be suspected as early as the first trimester, however the diagnosis cannot be excluded on the basis of normal ultrasound appearance until later in pregnancy.

Abnormalities, Multiple↗
PubMed1990

[Megabladder. Microcolon. Prenatal ultrasonic diagnosis and a review of the literature. Apropos of a case].

The condition of "megacystis-microcolon" is a very rare condition which can now be diagnosed ante-natally due to ultrasound. The presence of a megacystis (large bladder) with increased levels of amniotic fluid makes it possible to eliminate other ante-natal causes of dilatation of the bladder and in particular when it is found in a female fetus (as it is in 80% of cases). At birth, one finds, apart from the massive dilatation of the bladder with very little effect on the upper urinary tract, a microcolon with complete absence of peristalsis. This last abnormality always leads to a catastrophic short term result because treatment is quite ineffective. Many histological studies have been carried out and these sometimes differ from one another but it is possible to think that the condition is due to pathology of neurogenic origin in the muscle of the bladder and the aetiology of this is unknown. Finally, because there have been a few familial cases, there may be a genetic element in this illness that has such a poor prognosis.

Colonic Diseases↗
PubMedDate not supplied

[Thaumaturgical saints in phlebology in the Department of La Manche].

We have just studied the system of the Saints' illnesses in the French Manche area. This worship is still alive, as proves the number of requested masses. Formerly the medical density was low, the means of intellectual awareness (newspapers, television, rapid transport) did not exist. Medicine was rudimentary and expensive, so much so that in the case of sickness a person appealed to the Saints. In 1977, all these reasons ceased to exist and nevertheless people still appeal to them with the same fervour. How to explain the intensity and persistency of this devotion? Of course the Saints illnesses are the heirs of a far gone tradition and are part of a deeply-rooted regional folklore, but they mainly express the eternal disarray of man facing sickness. The human spirit needs hope to remain balanced just as the body needs food. The sick man can find this spiritual food by placing himself under the auspices of the healing powers, particularly under the Saints of the catholic religion and notably Saint Veronica, during vascular afflictions.

France↗