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Biomedical subjects

G Bock

Publications and source records attributed to G Bock.

At least 37 records · Page 2Linked to original sources

[Complications following duodenopancreatectomy in chronic pancreatitis].

42 partial and 5 total duodenopancreatectomies performed during the last ten years are reported. Complications--fistula, abscess, bleeding, insufficiency--occurred in 21 cases (46.5%). In 11 patients reoperation becomes necessary (23.4%) 6 patients died (12.7%). The advantages of primary partial duodenopancreatectomy comparing to other surgical procedures are discussed. Some surgical techniques in reducing the complication rate are recommended.

Abscess↗

The influence of D-penicillamine on cell proliferation. I. Quantitative investigations during an acute exudative inflammation in a model granuloma.

The influence of D-penicillamine (DPA) administration on a defined acute exudative inflammation in a model granuloma was investigated in a short-term experiment. The results indicate that DPA administration influences the metabolism of collagen but does not influence the proliferation behaviour of the fibroblasts. A significant increase in the number of fibroblasts can be explained in terms of an interaction of the loss of the soluble collagen with the number of fibroblasts necessary to maintain the total collagen level constant.

Animals↗

Skeletal muscle regeneration in myopathic hamsters of strain BIO 8262.

Skeletal muscle regeneration was studied in polymyopathic hamsters of the strain BIO 8262 by autoradiography. Flash labeling with 3H-thymidine revealed high labeling indices of mononuclear cells in areas with muscle cell necroses and low labeling of "interstitial cells". However, no labeled nuclei were present in myotubes. Three days after multiple injections of the radioisotope, labeled nuclei in the myotubes were present. The mean labeling intensity of these nuclei was slightly elevated on the 15th day. On the third day after multiple 3H-thymidine injections nearly all mononuclear cells were labeled; but their labeling indices slightly decreased until the 15th day. From the decrease of labeling intensity, a high turnover rate of these cells may be assumed. Labeled myotubes appeared in the neighborhood of mononuclear cells as well as in areas without pronounced round cell infiltrations. From labeled myotubes in areas with round cell infiltrations it may be concluded that they arose by fusion of rapidly proliferating satellite cells, which may be constituents of the mononuclear cell population. Labeled myotubes that appeared outside areas of mononuclear cell infiltrations may have been caused by fusion of slow proliferating satellite cells. Despite the fact of a high regeneration capacity of muscle in hamsters of the strain BIO 8262, this process is not sufficient to completely restore the muscle necroses.

Animals↗