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Biomedical subjects

G Bonavita

Publications and source records attributed to G Bonavita.

16 recordsLinked to original sources

Severity of anaemia and operative mortality and morbidity.

In a case-control study of 125 surgical patients who declined blood transfusions for religious reasons operative mortality was inversely related to the preoperative haemoglobin level, rising from 7.1% for patients with levels above 10 g/dl to 61.5% for those with levels below 6 g/dl. Mortality rates were also related to blood loss during surgery, rising from 8% for patients who lost less than 500 ml to 42.9% for those who lost more than 2000 ml. Both preoperative haemoglobin level and operative blood loss should be considered in assessing the need for preoperative transfusion. In our study no patient with a haemoglobin level above 8 g/dl and operative blood loss below 500 ml died.

Analysis of Variance↗

[Acute appendicitis: clinico-diagnostic and therapeutic considerations].

Since january 1970-december 1982, 58 patients underwent emergently appendectomy for acute appendicitis. 31 (53,4 percent) where males; the average age was 21 +/- 2,3 years (M +/- SEM). The duration of symptoms ranged from 1-6 hours (10,3 percent of cases) to over 48 hours, before the hospital admission (15,4 percent of cases). 27 patients (46,5 percent) had a clinical examination at home by a physician. 21 patients (36,4 percent) came to hospital emergency unit without previous physical examination; 10 (17,2 percent) were transferred from other departments. In 6,9 percent of cases was present a perforated appendicitis with peritonitis. During operation, in 50 percent of patients was performed a therapeutic peritoneal lavage. In 63,7 percent of cases multiple drains were placed in peritoneal cavity. In all patients was effected postoperative antibiotic profilaxis. The mortality rate was 3,4 percent. General complications were observed more in patients with perforated appendicitis. This review suggests the following remarcable data: morbidity of this disease is still high; the physical examination is more important than laboratory work (especially in the elderly patients, which are often immunodepressed and in children, with leucocitosis-lack at hospital admission); early surgery is the most important factor to the improvement of prognosis in these cases and the results of surgical treatment are improved by large vertical incisions, peritoneal lavage and application of multiple intracavitary drains.

Acute Disease↗

[Liver injuries. Clinico-diagnostic and therapeutic problems].

Out of 116 cases of abdominal trauma observed, 6 (23%) consisted of hepatic lesions. In 2 cases (33.3%) the hepatic lesion was isolated. In the other cases, it was associated with lesions to the diaphragm, duodenum, pancreas or thorax. After emphasis on the gravity of such lesions and the high mortality rate (33.3% in the cases observed) the factors contributing to the extremely gloomy prognosis are discussed and the basic therapeutic approach to injuries of varying gravity is outlined.

Adolescent↗

Risk factors for development of primary cancer in the gastric stump. Intragastric nitrites and nitroso-compounds after surgery for duodenal ulcer.

Results are reported from a study on the presence and concentration of nitrites and nitroso-compounds in the gastric juice of 53 patients operated on for duodenal ulcer and in 15 controls. The investigations were made after various postoperative intervals. In the patients who had undergone Billroth II operation, the concentrations of nitrites and of nitroso-compounds were higher than in those with Billroth I operation and in the controls. It is concluded that patients with Billroth II operation may be particularly susceptible to subsequent primary neoplasm of the gastric stump, as a result of the carcinogenic action of these substances.

Adult↗

[Traumatic lesions of the diaphragm (personal experience)].

From 1971 to 1982, 126 blunt thoraco-abdominal trauma were seen: in 9 cases (7,1%), diaphragmatic rupture was present. Automobile accidents were the most frequent cause of diaphragmatic rupture and, in only one case, the injury was single. Diaphragmatic rupture was suspected preoperatively in two patients, who had positive physical and radiologic chest findings. The lesion was seen intraoperatively in the other patients, who underwent surgical operation because of severe intra-abdominal injuries. In the author's experience, roentgenologic examinations and adjuntive studies were not important for diagnosis of diaphragmatic injuries. Surgical treatment depended on entity of associated intra-abdominal and intrathoracic injuries, especially in patients observed during immediate post-traumatic period. Authors conclude that single diaphragmatic injury, generally, give no surgical or prognostic problems. High mortality rate seen in these patients is due to multiple organ involvement.

Abdominal Injuries↗

[Cholelithiasis and peptic ulcer surgery. Personal experience (author's transl)].

In veiw of the interest represented by the possible development of cholelithiasis after peptic ulcer surgery, the authors report their results in 848 patients undergoing surgery for peptic ulcer, 521 were followed up in order to determine whether the biliary complication developed and in how many cases. They conclude that their results showed nothing which might support the possibility of the development of cholelithiasis after any from of surgery for peptic ulcer.

Adolescent↗