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Biomedical subjects

G Bottero

Publications and source records attributed to G Bottero.

At least 37 records · Page 2Linked to original sources
PubMed1980

[Gastric lesions in closed abdominal injuries (considerations on 8 cases)].

The Authors present 8 cases of traumatic lesions of the stomach, during the course of closed abdominal trauma, observed in the First Aid and Emergency Surgery Division of the Niguarda Ca' Granda Hospital, Milan, in the years 1970-1979. They take this as the starting point for a re-examination of the etiopathogenetic and anatomopathological data, and for diagnostic, prognostic and therapeutic considerations.

Abdominal Injuries↗
PubMed1980

[Considerations on two cases of spigelian hernia (author's transl)].

The Authors describe two cases of abdominal hernia through the linea semilunaris (spigelian hernia) of their own observation; they outline the anatomic substrate and clinical picture of this condition and conclude by advocating surgical correction as a constant indication.

Aged↗
PubMed1980

[Mortality and hospital complications of the myocardial infarction after dismissal from the coronary care unit (author's transl)].

259 patients affected by myocardial infarction were followed after their dismissal from the Coronary Care Unit. Monitoring rate, reached 14,3% as well as serious complications which were distributed equally during this period. Death was caused by cardiac decompensation (48.6%), serious arrhythmia (16.3%), cardiac break down (13.5%), repeated infarction (10.8%), sudden death (10.8%). In all cases the autopsy revealed serious cardiac damage and widespread coronary alteration. According to statistics, death and the onset of complications appear according to age 55 years, Peel's index 12, anterior infarction, presence of complications in the C.C.U. Important among such complications are: symptoms and clinical signs of decompensation, serious ventricular arrhythmia, advanced BAV and interventricular block. The AA. reached the conclusion for the necessity of installing areas of subintensive care for the benefit of subjects who presented serious complications during their stay in the C.C.U. (about 40% of the cases). It is foreseeable that these units will have twice as many beds as the C.C.U.

Adult↗
PubMed1978

[Variations of the pre-coronary times (1973-1977) (author's transl)].

A comparison has been made between the pre-coronary times of IMA patients in the UCIC of the S. Camillo Hospital in Rome between 1973 and 1977, and the pre-coronary times of patients in another UCIC in the same city, in order to record possible modifications. From 1973 to 1977 there has been a decrease in the pre-coronary times: this is the result of a better hospitalization policy and more frequent admission directly to the UCIC. The mortality rate according to the data in question, has also decreased from 21% in 1973 to 10% in 1977, with a marked reduction for patients with a pre-coronary time superior to 12 hours. This is also connected to the fact that there is a considerable reduction in the number of patients, generally suffering from serious complications, transferred to UCIC from other wards. From an analysis of the data we infer that there has been an improvement in the policy governing the admission of patients to UCIC, a policy which could be improved further by a more adequate training both for doctors and the population in general.

Coronary Care Units↗
PubMedDate not supplied

[Carcinoma of the male breast in the province of Alessandria. Clinico-pathologic aspects of an 8-years' case load].

The authors report their experience on male breast carcinoma based on a series of 16 cases diagnosed between 1981 and 1988 at the City Hospital of Alessandria. Main clinico-pathological findings are described and compared with those recorded in the relevant world literature. Emphasis is placed on the immunohistochemical evaluation of estrogen receptors and the frequency data of this uncommon cancer in hospital-based series are reviewed.

Adult↗
PubMedDate not supplied

Expression of epidermal growth factor receptor in human breast carcinoma and its correlation with morphological and biological features of tumour aggressiveness.

A series of 54 patients presenting with primary breast cancer were investigated for tumour expression of epidermal growth factor receptor (EGFR) by the indirect three-step immunoperoxidase technique which used the monoclonal antibody EGFR1. The percentage of malignant cells positive for EGFR was determined and scored on a four-point (0-3) scale in each case. EGFR was demonstrated in 35 (64.8%) tumours. EGFR expression did not correlate (p greater than 0.05) with growth fraction immunohistochemically visualized by means of the monoclonal antibody Ki-67, tumour size, axillary lymph node status and malignancy grade. In contrast, a significant inverse relationship (p less than 0.05) was found between EGFR and estrogen receptor (ER) patterns. Expression of EGFR per se does not appear to be relevant to the biological behaviour of breast cancer as revealed through an evaluation of proliferative activity, pathological stage and histological differentiation. Recognition that EGFR is negatively related to ER supports the present evidence that the control of malignant cell growth and differentiation depends on complex regulatory mechanisms in which several extracellular messenger molecules, including hormones and peptide growth factors together with their specific cellular receptors, are involved and inextricably interwoven.

Breast Neoplasms↗