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Biomedical subjects

G Boudreault

Publications and source records attributed to G Boudreault.

6 recordsLinked to original sources
PubMed1988

Static perimetry in canthaxanthin maculopathy.

We performed threshold static perimetry on 19 patients who had ingested canthaxanthin; 11 had maculopathy and eight did not. Patients with no history of canthaxanthin ingestion served as controls. All patients had visual acuity of 6/9 or better. Threshold static perimetry was reevaluated two to three years after cessation of canthaxanthin ingestion. For both testing sessions, patients with maculopathy presented lower retinal sensitivity than controls, while patients without maculopathy did not differ significantly from the control group. These results suggest that canthaxanthin retinopathy can adversely affect the neurosensory retina.

Adult↗
PubMed1987

Hibiclens keratitis.

Presumed accidental corneal exposure to Hibiclens (chlorhexidine 4% and detergent) in two patients resulted in severe and permanent corneal opacification. We investigated the corneal toxicity of Hibiclens by gross, biomicroscopic, and histopathologic studies of rabbit eyes exposed to Hibiclens for varying time intervals ranging from five to 15 minutes. Severe, irreversible, and progressive corneal damage resulted in all eyes studied.

Aged↗
PubMed1984

[Retinopathy due to canthazanthine: 2. Predisposing factors].

A retrospective study of 14 cases of retinopathy due to canthaxanthine, a carotenoid recently used as a skin-tanning agent, revealed that several clinical factors were associated with an increased susceptibility to retinal deposits: focal epitheliopathy, ocular hypertension and, possibly, the concurrent use of beta-carotene. Age has already been established as such a factor.

Adult↗
PubMed1983

[Canthaxanthine retinopathy: 1. Clinical study in 51 consumers].

Canthaxanthine, a non-provitamin A carotenoid, has been marketed in Canada since March 1979 as a skin-tanning agent. Fifty-one individuals who ingested from 3.6 to 66 g of the drug within a 24-month period were ophthalmologically evaluated. Six of them had deposits in the ocular fundus that appeared to be related to ingestion of the substance, but no functional impairment could be detected.

Administration, Oral↗
PubMed1982

[Maculopathy with golden particles].

This article describes two patients with a bilateral maculopathy due to the presence of numerous glistening yellow particles located mainly around the edge of the macular pit. This picture has apparently not been reported before. Further studies are needed to confirm a possibly toxic origin.

Adult↗