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Biomedical subjects

G Bronzi

Publications and source records attributed to G Bronzi.

8 recordsLinked to original sources

[Thrombophilia and thromboembolic disease. A case report].

Congenital thrombophilia, specifically thrombophilia due to Leiden modified factor V as the cause of thromboembolic disease, is discussed. Thromboembolic disease is potentially fatal and disabling. A clinical case is presented of a girl of 15 with Leiden factor V thrombophilia in which all the typical thromboembolic events occurred: superficial thrombophlebitis, rapidly developing deep venous thrombosis of an extremity and ischaemic arterial thrombosis of the distal arterial trunk of the same extremity. Systemic thrombolytic therapy done quickly cleared up the acute phase of the thromboembolic event without it being necessary to resort to thrombectomy and prevented post-thrombotic sequelae involving the extremity.

Adolescent↗

[Relapsing polychondritis. Review].

Using a clinical case which was brought to their attention as a starting point, the authors reexamine the problems relating to the nosographic, etiological, pathogenetic, pathoanatomical and clinical aspects of relapsing polychondritis, as well as those concerning its differential diagnosis and therapy. In particular, they review the various theories of immunological pathogenesis related to the alterations in collagen observed in relapsing polychondritis and in other correlated diseases.

Collagen↗

Neoplastic phlebothrombosis from renal vein to right atrium: a case report.

The authors present an atypical case of neoplastic thrombosis of the great abdominal veins, evaluated with echo-Doppler duplex scanner and computed tomographic scan with contrast enhancement. In this report the authors stress again the diagnostic accuracy of echo-Doppler methods in the study of such a phlebopathy. They describe its sonographic differential diagnosis from acute or chronic idiopathic phlebothrombosis.

Aged↗

[Idiopathic hypereosinophilia syndrome: description of a clinical case and review of the literature].

Idiopathic hypereosinophilia is a disease with an unknown etiology and pathogenesis and uncertain nosographic classification, although there is now tendency to group a number of syndromes under this name which were previously classified separately, although having similar hematological symptoms and clinical manifestations. The paper examines these aspects and reports the case of a patient with idiopathic hypereosinophilia to steroid treatment.

Diagnosis, Differential↗

[Role of non-invasive vascular diagnosis in the study of "diabetic foot"].

The Authors examine the possibilities of instrumental diagnosis in patients with the "diabetic foot" syndrome. The lack of clinical relevance of the so called "microangiopathy" is stressed, because. Indeed, either the "macroangiopathy" or the diabetic neuropathy are responsible for almost all the symptoms of this syndrome. In the differential diagnosis between these two major sequelae of diabetes, with consequently wide differences in the therapeutic choices, the Doppler ultrasound examination has been of paramount usefulness, because it is very sensitive and specific in detecting and localizing any lesion suggestive of macroangiopathy.

Diabetic Angiopathies↗

[Hyponatremia in cirrhosis with ascites].

Hyponatremia complicates ascitic hepatic cirrhosis with frequency and gravity related to the gravity of the cirrhosis itself. When hyponatremia develops, it worsens the already present secondary hyperaldosteronism and makes therapy with spironolactone inefficacious. From a pathophysiologic viewpoint a pathogenetic role in determining hyponatremia is attributable to the reduced plasmatic renal perfusion; in several patients a syndrome of inappropriate ADH secretion develops. Other neurohormonal systems (catecholamines, prostaglandins, natriuretic hormones) are probably very important in modifying renal hemodynamics and renal tubular function. In some patients a causative role for hyponatremia is attributable to iatrogenic factors (e.g.: diuretics). From a therapeutic viewpoint, we examine some schedules, pharmacologic or not, that, however, are far from being useful for all patients. We discuss, mainly, water restriction, osmotic diuretics with or without loop diuretics, loop diuretics followed by sodium reintegration and concentration-reinfusion of ascites or application of peritoneovenous shunt.

Ascites↗

Thrombosis of congenital double popliteal vein: case report.

The authors present the case of a patient with phlebothrombosis of the left lower limb, not diagnosed with traditional ultrasonographic methods (Doppler c w) but recognized by the echo Doppler (duplex scanner) method. The diagnosis was made difficult by the presence of a congenital double left popliteal vein, with hypoechogenic thrombosis of only one of the two twin veins. The authors stress the diagnostic importance of the duplex scanner method in the study of the phlebobstructive pathologies of the lower limbs.

Humans↗