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Biomedical subjects

G Broussard

Publications and source records attributed to G Broussard.

18 recordsLinked to original sources

Bilateral transverse sinus stenosis predicts IIH without papilledema in patients with migraine.

BACKGROUND: The headache profile of patients with idiopathic intracranial hypertension without papilledema (IIHWOP) may be indistinguishable from that of migraine. Bilateral transverse sinus stenosis (BTSS) has been found in the majority of patients with IIHWOP. The frequency of BTSS associated with IIHWOP in patients with migraine is unknown. OBJECTIVE: To detect the frequency of BTSS in adult patients with migraine and to investigate whether the presence of BTSS identifies patients with IIHWOP. METHODS: In a prospective study from December 2000 to November 2005, 724 consecutive patients with recurrent headaches who fulfilled International Headache Society diagnostic criteria for migraine underwent cerebral MR venography (MRV). A portion of these patients underwent a lumbar puncture (LP) to measure CSF pressure. MRV and LP were also performed in 70 age-matched control subjects. RESULTS: Six hundred seventy-five of the 724 patients with migraines had normal MRV. Seventy of these 675 patients underwent LP, and all of them had normal CSF pressure. Forty-nine (6.7%) of the 724 patients with migraine had BTSS. Twenty-eight of these 49 patients with BTSS underwent LP, and 19 (67.8%) had IIHWOP. The headache profiles of patients with BTSS and IIHWOP did not differ from those of patients with normal MRVs and CSF pressures within normal limits. CSF pressure was normal in both patients and controls with normal MRV. CONCLUSIONS: Of patients with migraine, 6.7% had bilateral transverse sinus stenosis; 67.8% of these patients had idiopathic intracranial hypertension without papilledema (IIHWOP). These results suggest that patients with migraine who present bilateral transverse sinus stenosis on cerebral MR venography should undergo lumbar puncture to exclude IIHWOP.

Adult↗

Triangular wire.

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Humans↗

Occupational risk and toxicology evaluations of industrial water conditioning.

This study addresses the chemical and toxicological questions due to the wide use of chemical treatment programmes for industrial cooling water. First, natural problems encountered in cooling tower systems were presented and grouped into three categories: (i) scaling; (ii) corrosion and (iii) biofouling. Chemical solutions adopted in industrial plants were outlined for each one in order to minimize damage and categorized as shut-down, production loss, heat transfer reduction, upsets, etc. Above all, the purpose of the work was to identify the most dangerous chemicals normally used, which means sources of chemical risk for safety workers and their environment; thus, symptoms of exposure, prevention measures and protection tools are also described.

Corrosion↗

Chemical technology for the toxic gas flow control through process water system.

The aim of this work is focused on the safety and toxicological aspects due to under-pressure industrial plant management, above all in the case which the gas is very dangerous for human health and environment. Here is illustrated the safe method of control of risks through specific choices of engineering devices and chemical process: in this way we have shown the mathematical calculation regarding the case of ammonia flow gas running in the piping and plant under-pressure. In this paper the Authors show the assessment of the technological solution for falling down of a toxic gas as NH3, which lets off from safety values facilities. The under pressure industrial plants with ammonia are protected through the safety valves, settled at 20 bar pressure. The out-let gas flow is capted by a tank of a water bulk of five time theoretical water amount necessary to the complete absorption of gas. In order to prevent any health risk and carry out a safety management, it needs to verify two basic aspects, with connected specific techniques: 1. The safety valves technology through the mathematical calculation of operating device; 2. The absorption process of the toxic agent for controlling of dangerous runaway of gas.

Air Pollutants↗

[Environmental study on toxicity of water resulting from pesticide and biocide pollution].

A chemical product has a level of danger or security which depends on the concentration and on the exposure time. The toxicity of the water is established by the answer (survival) of an animal organism in contact with a specific chemical product in short time. There are several reliable methods in the world; in any case the most significant aspect is given by the mortal concentration of the substance (mg/L) in connection with the organism dimensions. Among the methods we can point out:--% of mortality;--N.O.E.L. (No Observed Effect Level);--LC50. We must know the following data too:--responsable for the product;--registration of the pesticide/biocide;--risk valuation;--T.E.R. (Toxicity Exposure Ratio);--P.E.C. (Predicted Environmental Concentration); measures of detoxication;--ratio product toxicity/usage. The chronic effects concern the health the growth, the survival and the reproduction. These data are used for the management of the risk, the preparation of chemical substance in security, the treatment of accidental poisoning, the determination of TLV and safety level (LD50-LC50) of the substances (pesticide, biocide).

Environmental Monitoring↗

[Test of pharmacologic bronchial stimulation in the assessment of work suitability].

The suitability to the work is one of the main items of occupational medical doctor's activity, often developed with very few informations about the effective features a worker is about to carry out. Consequently, every appraisal of work suitability is based almost exclusively on clinical analysis. A peculiarity of the problem is the one strictly connected with the Allergic Pathology, since it brings a condition in which the subject under medical exams don't present any operative-limiting pathological condition; he could, anyway, presents a slight limitation connected to a subjective response toward a eventually workplace-based specific allergenic agent. It's important, therefore, the need to show, in case of workers exposed to potentially allergenic substances, that subjective conditions who could cause an abnormal reactivity in presence of a potentially efficient stimulation. The main intention of this piece of work is to develop a study about the utility of bronchial challenge with methacoline in a context of evaluation of work suitability for those allergenic substances exposed jobs.

Adult↗

[Aromatic polycyclic hydrocarbons: chemism, vehicles and technics for protection from toxicological risk].

In this work we take under examination the aromatic polycyclic hydrocarbons (APHs) as a class of organic micropolluting agents which have a considerable impact in the life and in the working environment of man. The authors decided to expressly start this study by proposing the changes pattern cause by APHs according to their chemical-physical reactivity characteristics, in order to realise a qualitative and quantitative evaluation of their toxicologic impact. Therefore, the specific aspects of chemism (reactions of substitution, aromatic electrophilia and addition) of these organic micropolluting agents are studied with particular reference to their chemical structure and to the properties which are the main important cause of every effect of diffusion both in productive environments and of toxicity in the human body. In this way, come toxicologic risk sources, responsible, within some technological cycles for the APHs emission in the working areas, are identified, shown and evaluated; carrying factors, not much investigated till now, which represent a synergic effect to the introduction and absorption of the APHs by the human body. For the necessity of a useful environmental monitoring which could be applied to different matrices, the techniques and the methods useful for carrying out sampling and analytical evaluation in a correct way, are introduced as well. Lastly, the Authors stress on the engagement and discuss the measures of prevention and protection, technically performable on the basis of the chemico-physical-granulometric properties of APHs, with the goal of safeguarding at best health of people occupationally exposed.

Air Pollutants, Occupational↗