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Biomedical subjects

G C Botta

Publications and source records attributed to G C Botta.

54 records · Page 3Linked to original sources
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[Vascular homografts: clinical results].

The authors review the results of clinical experiences regarding arterial and venous homografts. For the treatment of mycotic aneurysms and infected prostheses, in situ repair with vascular homografts represents a valuable alternative to conventional surgical treatments. In fact the large caliber arterial homografts allow safe in situ reconstruction, decrease early and midterm mortality and reinfection rates; the best results are achieved in case of infected grafts, whereas the prognosis of vasculo-enteric fistula remains very poor. The small caliber arterial homografts also have demonstrated satisfactory results in term of patency, although further experiences with longer follow-up are required. Vein homograft constitutes an alternative by-pass conduit for limb revascularisation in patients who lack adequate autogenous vein: although limb salvage rate is satisfactory, long term patency rate is poor when compared with autogenous veins. Improvement of preservation methodics, pharmacological control of rejection and tissue engineering represent the future perspectives in this field.

Blood Vessels↗
PubMedDate not supplied

[Asbestos fibres and reference values].

Biological RV for asbestos implies several problems, due to the difficult interpretation of values obtained from various biological samples (sputum, BALF, lung tissue). Therefore, it seems it advisable to refer to environmental concentrations (ERC), which are not avoidable, since asbestos is an ubiquitous contaminant. On the basis of the available studies the 1 f/L value is usually reported as the most representative, although more recent and reliable studies would indicate lower values, at least for outdoor concentrations, as determined by SEM. However, further studies are needed: standardized methods based on SEM (author's opinion) should be adopted; the accuracy of such technique is sufficient for air concentrations from 0.05-0.1 f L-1 upwards, with the advantage of lower costs and time as compared to TEM.

Asbestos↗
PubMedDate not supplied

Stenosis of the carotid artery and thrombosis of the internal contralateral carotid. Analysis of surgical results in thirty patients.

Carotid thrombosis and stenosis of the contralateral axis is a hemodynamic situation which results in reduced blood supply to the brain, and consequently in risk of transitory or permanent ischemic episodes. In fact, 40% of patients are symptomatic for TIA or Little Stroke and 50% of them will develop a complete stroke. Of the 255 patients who underwent TEA, over a period of 5 years, only 30 presented the above mentioned bilateral feature. A continuous electroencephalographic recording (EEG) was intraoperatively carried on for cerebral monitoring, as well as mean residual arterial pressure (MRAP), and according to variations in these parameters Javid's shunt was used in 50% of cases. No death was recorded either during surgery or hospitalization, while 2 transitory post-operative neurological deficits (6.6%) in correspondence to the stenotic vessel, and a late permanent deficit contralateral to the stenosis were reported. We believe TEA of the stenotic carotid artery to be a rational choice considering the great incidence of strokes on the stenotic side (Grillo, 1975) and the greater benefit for patients with symptoms resulting from the occluded carotid (Riles, 1980), who account for 46.6% of our case histories. We are convinced that surgery is an absolute indication in this particular category of patients, even at the cost greater intraoperative risks, provided it is carried out by an experienced surgical team well aware of problems involved in intraoperative cerebral monitoring.

Carotid Artery Diseases↗
PubMedDate not supplied

Carotid occlusive disease: an electrophysiological macular investigation.

Thirteen patients with carotid stenosis were studied by the authors by the measuring the Visual Evoked Potentials (VEPs) before and after thromboendarterectomy. This test of retinal function measures the recovery time of the amplitude of the major positive peak (P100) after photostress. When compared to that we observed in controls, we found, a significant increase of the P100 recovery time in patients suffering from carotid disease with severe stenosis. The method proved suitable for the functional evaluation of the vascular reconstruction of the carotid area, since four weeks after surgery a physiological recovery of the amplitude of VEP was observed. This method is proposed by the authors for the long-term functional evaluation of patients subjected to carotid thromboendarterectomy for tight stenosis of the carotid bifurcation.

Aged↗
PubMedDate not supplied

[Treatment of esophageal achalasia].

4 cases of oesophageal achalasia, 2 primary and 2 recurrences following multiple oesophagomyotomy are reported. The superiority of oesophagomyotomy carried out by the left transthoracic route (according to Ellis) in cases of primary achalasia is stressed. On the basis of the literature and reported experience, it is concluded that this approach is also preferable in recurrences when the previous operation was done by the abdominal route and the recurrence occurred within 6 months. In all other cases, particularly in the presence of an achalasic megaoesophagus, partial oesophagogastric resection with interposition of a jejunal loop (Merendino's operation) is the procedure of choice and the satisfactory results of using it are reported.

Adult↗
PubMedDate not supplied

Abdominal aortic aneurysms: some controversial points.

A retrospective review of the surgical treatment of 51 abdominal aortic aneurysms is reported. Thirty-five (69%) patients were operated on electively, and 16 (31%) had emergency surgery. Fissurated aneurysms were included in the elective surgery group. The operative death rate was respectively 2.7% and 50%. Controversial points about diagnosis, treatment of associated diseases, surgical technique, and selection of the patients for surgery are presented and discussed.

Aged↗
PubMedDate not supplied

[Emergency resections of the left colon with immediate reconstruction protected by resorbable staples. A new possibility tested on animals].

Anastomosis recovery still represents a problem in colon surgery, particularly when the resection is performed in emergency or on a suffering and not adequately prepared bowel. The authors describe a new technique successfully tested in the animal. The operation consists in a bowel resection followed by immediate reconstruction with a protective colostomy and an exclusion anastomosis obtained by a proximal suture in resorbable clips. Results in animals have been satisfactory, with a spontaneous and gradual resumption of physiological canalization, according to authors expectations. Technical details and several histological features are herein described.

Absorption↗