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Biomedical subjects

G C Piazza

Publications and source records attributed to G C Piazza.

6 recordsLinked to original sources

"Pure" traumatic cerebral lacerations. A review of 129 cases with long-term follow-up.

The authors present a series of 129 patients with "pure" traumatic cerebral lacerations, i.e. not associated with other intracranial lesions (especially haematomas) which by their presence alone can play a primary role in affecting clinical course and prognosis. Twenty per cent of the patients presented a lucid interval, thus confirming the nature of the laceration as a true expanding lesion, increasing in size in the post-traumatic period. Age, GCS score and neuroradiological findings were investigated in view of the eventual outcome. Follow-up examination confirmed that age and level of coma on admission, together with the degree of ventricular shift and presence of bilateral skull fractures, were all factors of statistical significance in affecting prognosis. Lacerations in the temporal area were associated with the poorest prognosis, and highest incidence of neurological focal deficits and residual parenchymal damage on CT control.

Adolescent↗

Programmed serial CT scans in the surgical and radio-chemotherapeutic management of cerebral gliomas.

On the basis of a 4 year experience with CT scan in cerebral gliomas and of previous personal contributions in this field, a neuroradiological protocol of these patients is proposed. The protocol consists of a complete preoperative neuroradiological evaluation and of CT assessments at the end of the surgical procedure, before initiating radio-chemotherapy, and at the completion of each of its cycles, respectively. Attention is drawn to the importance of contrast enhancement, to the role played by the changes in the blood-brain barrier (BBB), either due to surgery or to the effect of radio-chemotherapy and to the identification of residual tumor or of recurrences. CT scan to be performed at the end of the operation is proposed on the assumption that, in spite of the increased possibility of artifacts due to blood, air, etc., it may provide an immediate and better evaluation of the surgical results as compared to the CT picture at the beginning of radio-chemotherapy, when changes in the patient's brain may already have occurred.

Brain Neoplasms↗