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Biomedical subjects

G C Pritchard

Publications and source records attributed to G C Pritchard.

36 records · Page 2Linked to original sources
PubMed1992

Natural scrapie in goats: case histories and clinical signs.

The case histories of the 20 goats affected with natural scrapie which have been examined since 1975 at the Central Veterinary Laboratory, Weybridge, are reviewed. Their ages ranged from two to seven years (median three years, four months) and 85 per cent of them were between two and four years old. The most common clinical signs were hyperaesthesia, ataxia and pruritus. The histories indicated that scrapie can occur in goats which have not been in contact with sheep.

Animals↗
PubMed1990

Concurrent maedi-visna virus infection and pulmonary adenomatosis in a commercial breeding flock in East Anglia.

The seroprevalence of maedi-visna virus infection in thin potential cull ewes aged over two years in a flock in East Anglia increased from 3.7 per cent in August 1985 to 39.0 per cent in September 1987 and 93.3 per cent in May 1989. This increase coincided with the first appearance of sheep pulmonary adenomatosis in the flock. Four emaciated ewes which were dyspnoeic were necropsied between 1987 and 1989. Maedi and pulmonary adenomatosis were confirmed histologically in one of these ewes and pulmonary adenomatosis was confirmed in the other three.

Animals↗
PubMed1989

Severe disease in a dairy herd associated with acute infection with bovine virus diarrhoea virus, Leptospira harjo and Coxiella burnetii.

Between November 1984 and February 1985, a serious outbreak of pyrexia, diarrhoea, agalactia, metritis and severe weight loss affected most of the recently calved cows in a 183-cow dairy herd in Norfolk. Fifteen cows died and 20 were culled. Forty cows aborted during or after the outbreak, and many of them produced mummified fetuses; 18 calves were stillborn and three others died soon after birth. Necropsy of three affected cows revealed ulceration of the gastrointestinal tract similar to that seen in cases of mucosal disease. Bovine virus diarrhoea virus was isolated from the intestines of one cow that died soon after the onset of illness. The virus was also isolated from the blood of four acutely ill cows and seroconversion was demonstrated in three of those that survived. The virus was isolated from three aborted fetuses, a stillborn calf and a live neonatal calf. Body fluids from two aborted fetuses were seropositive for the virus as were sera from all the aborting cows tested. In addition to widespread seroconversion to bovine virus diarrhoea virus during the outbreak, there was serological evidence of recent infection with Leptospira interrogans serovar hardjo and Coxiella burnetii in a high proportion of cows. It was concluded that this was primarily an acute outbreak of bovine virus diarrhoea but its unprecedented clinical severity was probably associated with the concurrent introduction of L hardjo and C burnetii into an immunologically naive herd during the main calving period. Epidemiological analysis suggested that the source of the virus and L hardjo was down-calving heifers returning from communal marsh grazing.

Abortion, Veterinary↗
PubMed1987

Transmissible gastroenteritis in endemically infected breeding herds of pigs in East Anglia, 1981-85.

Endemic infection was a common sequel to primary outbreaks of transmissible gastroenteritis in large breeding herds of pigs in East Anglia. The main clinical features of the disease were diarrhoea affecting sucking piglets aged about six days or more, diarrhoea among recently weaned pigs and brief episodes of overt clinical recrudescence in part of the herd. Post mortem and bacteriological findings were often more suggestive of colibacillosis than transmissible gastroenteritis. In some herds, endemic infection remained clinically mild or inapparent for long periods. Evidence of endemic transmissible gastroenteritis infection was found in 43 (50.6 per cent) of 85 herds of pigs studied prospectively between 1981 and 1983. There was a significant correlation with herd size; the disease recurred during the 12 months after primary outbreaks in 36 (65.5 per cent) of 55 herds with over 100 sows compared with seven (23.3 per cent) of 30 herds with less than 100 sows (P less than 0.001). In the larger herds it occurred more commonly where finishers were kept (P less than 0.05). Sow morbidity and management factors during the primary outbreak had no statistically significant effect on the incidence of recrudescence. Epidemiological aspects of the findings are discussed with emphasis on the difficulties associated with the diagnosis and control of endemic transmissible gastroenteritis infection.

Animals↗
PubMed1985

Zinc toxicity, copper deficiency and anaemia in swill-fed pigs.

Zinc toxicity, copper deficiency and an associated anaemia among weaned swill-fed pigs is described. The source of zinc was flaking galvanising from the inside of bins used to store swill before processing. The disease condition readily responded to supplementation of the diet with copper sulphate. The interactions between dietary zinc, copper and calcium are discussed with reference to the swill-feeding industry. It is concluded that supplementary copper should be routinely included in the ration of swill-fed pigs and that the use of galvanised bins for storing swill should be avoided.

Anemia↗
PubMed1983

Alopecia in calves associated with milk substitute feeding.

Outbreaks of alopecia with unusually high morbidity occurred among calves reared on milk substitutes on two unrelated farms in Suffolk. On one farm alopecia occurred for three consecutive years; during the winter of 1981-82 there were also clinical signs of muscular dystrophy among the same calves. On the second farm calves with alopecia also showed signs of muscular dystrophy. The apparent relationship between alopecia and milk substitute feeding is discussed together with the possible involvement of vitamin E.

Alopecia↗
PubMed1982

TGE of pigs.

Explore the source record for details and available documents.

Animals↗
PubMed1982

Observations on clinical aspects of transmissible gastroenteritis of pigs in Norfolk and Suffolk, 1980-81.

Outbreaks of transmissible gastroenteritis in 56 breeding units, six maiden gilt sites and 64 fattening units were investigated during the period December 1980 to October 1981. The disease invariably occurred in classical virulent form, resulting in very high mortality in baby piglets. Reproductive sequelae were sometimes evident. Individual outbreaks continued for longer than in previous years. There was a high rate of recrudescene, particularly in large breeding units, and infection also persisted in many fattening units. The value of control measures and supportive therapy is discussed.

Abortion, Veterinary↗
PubMed1980

The distribution of Mycoplasma meleagridis in normal turkey carcases and those affected with air sac disease.

Mycoplasma meleagridis was isolated from both normal and diseased air sacs of turkeys examined and graded for air sacculitis on the evisceration line in a processing plant. It was also cultivated from wing bone cavities of turkeys with severe air sac lesions but not from leg bones or from samples of deep muscle. A further investigation, using material taken randomly from the condemned meat container, confirmed that M meleagridis was recoverable from wing bones.

Air Sacs↗