Biomedical subjects

G C Santos

Publications and source records attributed to G C Santos.

20 records · Page 2Linked to original sources

PubMedDate not supplied

[Jejunal myenteric denervation induced by benzalkonium chloride].

The effects of benzalkonium chloride (BAC) on the number of myenteric neurons, muscle thickness and external perimeter after acute (until 10 days after BAC application) and chronic (30 and 60 days after BAC application) denervation of the proximal jejunum were determined in rats. There was a significant reduction in the number of myenteric neurons of all segments treated with BAC. The extent of denervation varied along the time, and it was reduced in the denervated segments of the chronic group in comparison with the acute group. This may be due to the neuroplasticity phenomenon appearing during the chronic phase. Myenteric denervation increased the thickness of the propria muscle layer, especially in the longitudinal muscle layer, suggesting a higher sensitivity of this layer to myenteric denervation.

Animals↗

PubMedDate not supplied

[Gastrointestinal endocrine cells: brief history and main identification methods under light microscopy].

The gastrointestinal tract shows a wide spectrum of endocrine cells diffusely distributed along the mucosa, interspersed among the exocrine cells. These cells share several features such as the capacity to produce a series of peptides. Despite the development of digestive endocrinology, especially in the last decade and with respect to the biochemical knowledge and cellular localization of gastrointestinal regulatory peptides, their functional significance and their role in digestive phisiopathology remain partially unknown. This review represents a summary of the principal information about morphological and histochemical features, embryologic origin, historical data, methods of identification and types of endocrine cells, of gastrointestinal tract.

APUD Cells↗