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Biomedical subjects

G Cardini

Publications and source records attributed to G Cardini.

At least 19 recordsLinked to original sources
PubMed1998

Survey of keratinophilic fungi isolated from city park soils of Pisa, Italy.

A survey of geophilic dermatophytes and related keratinophilic fungi isolated from city park soils of Pisa is reported. Twenty-three (48%) soil samples out of 48 were positive by hair baiting. The following species were isolated: Microsporum gypseum (39%), Trichophyton ajelloi (31%), Chrysosporium keratinophilum (14%), T. terrestre (8%), M. fulvum, Ch. luteum, Ch. indicum (5% each) and M. cookei (2%). The presence of the different species is discussed in relation to the risk of fungal skin infections.

Arthrodermataceae↗
PubMed1996

Delta-aminolevulinic acid dehydratase and zinc protoporphyrin in very low lead-exposed pets: a community study.

Markers of lead intoxication have been developed based on their capacity to identify lead intoxication at the preclinical, ie biochemical stage of manifestation. However, little information on these markers is available under conditions of low lead exposure. This prompted us to conduct a community-based study to determine the usefulness of theta-aminolevulinic acid dehydratase (ALAD) and zinc protoporphyrin (ZnPP) in conditions of low lead environmental exposure by studying the relationships between low blood lead levels, ALAD and ZnPP in a large group of healthy dogs living in an Italian urban area. The study population consisted of 79 dogs. Each sample was tested for ALAD, lead and ZnPP and for complete blood count, hemoglobin, AST, ALT, and urea values. A weak inverse relationship between ALAD and ZnPP was found. An inverse relationship between ALAD and lead concentrations was found in the whole group (p < 0.0005). This relationship remained significant when selecting the values falling between 2 standard deviations of the mean blood lead concentrations of the population below the "concerned lead levels" (< 10 mg/dl; p = 0.0005). There was no relationship between whole blood ZnPP concentrations and whole blood lead levels. The sensitivity and specificity of ALAD measurements, calculated by using the 2 x 2 contingency table with respect to blood lead concentrations, were of poor predictive diagnostic value.

Animals↗
PubMed1994

Experimental infection of dogs with Borrelia burgdorferi.

Four beagle dogs were inoculated subcutaneously with the BITs1 Italian strain of Borrelia burgdorferi. Only one dog became infected and B burgdorferi was isolated from its blood and urine three and four weeks after infection. B burgdorferi antibodies were detected by immunofluorescence from four to 11 weeks after infection. An uninoculated dog kept in the same run as the infected dog, developed a positive serological response, but none of the five dogs showed clinical signs.

Animals↗
PubMed1989

Evaluation of the JT and corrected JT intervals as a new ECG method for monitoring doxorubicin cardiotoxicity in the dog.

A comparison was made of the sensitivity of ECG, ultrastructural heart pathology, and plasma enzymes CK-MB and alpha-HBDH as methods to assess doxorubicin cardiotoxicity in adult beagle dogs given doxorubicin 30 mg/m2 i.v. once a week for three times. A progressive increase in JT and QT intervals, in corrected JT (JTc) and QT (QTc) intervals as well as a reduction in both T wave amplitude and RR duration, were observed in doxorubicin-treated dogs; the electrocardiogram (ECG) abnormalities were associated with doxorubicin-induced ultrastructural changes in cardiac tissue, consisting of dilation of the sarcoplasmic reticulum, multiform, flasklike invaginations of T-tubules containing electrondense material, and interruption of the junctional sarcoplasmic reticulum, which became more severe as the observation period progressed. On the contrary, doxorubicin treatment was associated with transient changes in plasma CK-MB and alpha-HBDH, which were unrelated to the severity of chronic cardiotoxicity. Overall results suggest that the monitoring of the ECG parameters related to the repolarization of the cardiac muscle, and particularly JT and JTc, might be regarded as a noninvasive method for the study of doxorubicin cardiotoxocity in the dog.

Animals↗
PubMed1980

The use of methanol-grown yeast LI-70 in feeds for broilers.

In 60-day feeding trials, broilers were fed commercial diets in which different amounts of methanol-grown yeast LI-70 replaced fish and soybean meal. In the first trial, all-mash diets containing up to 15% yeast produced growth rates and efficiencies of feed conversion almost equal to those of the soybean meal control and slightly below those of the fish meal control. In the second trial, pelleted diets containing up to 25% yeast were used. For yeast levels up to 15%, growth rates were faster than for the soybean meal control and slightly slower than for the fish meal control. Diets with more than 15% yeast lacked selenium. Diets containing 25% yeast as the sole source of protein but supplemented with .3 ppm selenium produced growth rates and efficiencies of feed conversion equal to those of the controls.

Animal Feed↗
PubMed1976

Taxonomical examination and characterization of a methanol-utilizing yeast.

The morphological, cultural, and physiological characteristics are described of a yeast, LI70, which uses methanol as its source of energy and carbon; these characteristics have made it possible to identify the strain as Candida boidinii Ramirez. The identification was confirmed by a DNA-DNA genetic homology of 99.43% with the type strain of C. boidinii. Strain LI70 is not pathogenic.

Animals↗
PubMed1975

[Double clone in cells of pleural effusion caused by metastasis of oat cell carcinoma of the lung].

The Authors report a chromosome study carried out on pleural effusion cells from metastases of oat cell carcinoma. They observed a double cell clone: the former, with 44 chromosomes, with various alterations of the karyotype and a big acrocentric "marker", the latter, with 45 chromosomes with various alterations of the karyotype and a big submetacentric "marker". From these observations the Authors draw some interpretative considerations.

Antibody Formation↗