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Biomedical subjects

G Carlomagno

Publications and source records attributed to G Carlomagno.

At least 19 recordsLinked to original sources
PubMed1996

Efficacy and tolerability of brodimoprim at two different dosage schedules in the treatment of acute uncomplicated bacterial cystitis: comparative study vs. pefloxacin.

In an open study, 172 male and female adult patients with acute uncomplicated bacterial cystitis were randomly allocated to three treatment groups. Two groups received brodimoprim 200 mg tablets as follows: a single dose of two 200 mg tablets on day 1, followed by one tablet per day on days 2 and 3 (58 patients); or a single daily dose of two tablets, for 2 days (63 patients). The third group received a single dose of pefloxacin, as two 400 mg tablets, for 1 day (51 patients). Complete urinalysis, sediment and urine culture examinations were carried out before treatment and 10 days after the last dose. Evaluation also comprised, at the time of enrolment and 48 h after the last dose, measurement of corporal temperature and assessment of symptoms (dysuria, pollakiuria, strangury, suprapubic pain, burning sensation during urination and urgency) on a 4-point scale. The eradication rate for the pathogen concerned was 98.3% and 96.7% in the groups receiving brodimoprim for 3 and 2 days, respectively, and 92.8% in the pefloxacin group (between-group comparison n.s.). There was significant regression of symptoms (P < 0.001) in the three groups (between-groups comparison n.s.). Mainly gastrointestinal adverse events occurred in 3 patients receiving brodimoprim for 2 days and in 4 patients from each of the other two groups.

Acute Disease↗
PubMed1996

Postmaturity: how far is it a clinical entity in its own right?

In 1990 we adopted a protocol of antepartum testing for all booked pregnant patients, permitting healthy pregnancies to go beyond 42 completed weeks of gestation. This retrospective study regards 84 patients delivering after 42 completed weeks of pregnancy and a control group of 1351 patients delivering after 37 completed and before 41 completed weeks of pregnancy. Records were revised for maternal age and parity, previous obstetric history, managing and complications of the actual pregnancy, labour and mode of delivery, neonatal biometric data and outcome. Only 4 patients delivered after 43 completed weeks of gestation, while none in the series delivered later than 44 completed weeks after the beginning of the last menstrual period. The overall frequency of caesarean birth was higher, but not significantly, in study group. Average neonatal birthweight and length were significantly greater in the study group. No significant difference in neonatal outcome was observed between study and control groups in terms of perinatal mortality. Low 1' Apgar score was significantly more frequent in the study group, but a similar frequency of 5' Apgar score and need for intensive care was observed in the two groups.

Adult↗
PubMed1995

[Bleeding gastric leiomyoma: diagnostic error solving an emergency case].

Although rare, benign gastric tumours are frequently encountered in the recent years thanks to the greater accuracy of diagnostic investigations. The Authors report their experience in a case of bleeding gastric leiomyoma which caused preoperative diagnostic problems due to the extraluminal development of the tumor and to diagnostic investigation errors. An easy diagnosis of this type of tumor is not therefore a rule, but, as in the case reported, may be rather insidious especially in small leiomyomas with an extra or intraparietal development and aspecific symptomatology masquereding other more frequent pathologies.

Aged↗
PubMed1991

Management of labour following caesarean section in a developing country.

During recent years, the observed rise of the CS rate (17% in 1989) led the medical staff of the Maputo Central Hospital to consider the opportunity of admitting to trial of labour selected pregnant patients following one previous CS. The present study retrospectively evaluates maternal and fetal outcome following the adoption of this policy. 94 (52.51%) of 179 study group patients, having one previous CS, delivered vaginally after trial of labour. No maternal deaths were recorded among these patients. A very low (1.67%) maternal morbidity rate was observed. Five stillbirths and one early neonatal death occurred among the study group, accounting for a perinatal mortality rate of 33.52%, much lower than the overall hospital perinatal mortality recorded figure (68%).

Delivery, Obstetric↗
PubMed1989

[Administration of uterotonic drugs at the end of the expulsion stage. Comparison of the use of oxytocin and ergometrine maleate].

In spite of the large diffusion of uterotonic drugs some doubts persist about which preparation and which dosage are the most suitable. For such a reason a group of pregnant women, to whom ergometrine maleate was administered at the delivery of the anterior shoulder of the fetus, was compared by the authors to an analogous group formed by pregnant women to whom oxytocin was administered under the same conditions. Pregnant women not submitted to a pharmacologic control of the third stage of labour served as a control group. Each study group was thereafter divided into 2 subgroups: the former is composed by patients submitted to episiotomy and the latter by patients not submitted to this procedure. Our results have shown the usefulness of both drugs in the active management of the third stage of labour, whereas different side effects may occur.

Episiotomy↗
PubMed1989

[Obstetrics in Somalia. Maternal and infant mortality in the metropolitan area of Mogadishu. The current situation and future prospects].

Maternal and infant mortality in Somalia are very high: the obstetric situation of the country in relation to socioeconomic conditions is presented. The factors responsible for this tragic situation are outlined critically and, finally, the essential points of a pilot project aimed at lowering maternal mortality for obstetric causes from current levels (1,100/100,000 live births) which cannot be accepted even in a developing country, are summarised.

Female↗
PubMed1989

Advanced non-tubal ectopic pregnancy at the "Hospital Central" of Maputo (Moçambique).

The authors report clinical data and pathological findings from a series of 13 cases of non-tubal ectopic pregnancies which occurred at the Hospital Central of Maputo (Moçambique), during a 14-month period. The rather high frequency of abdominal pregnancy (6 cases diagnosed during the third trimester of gestation) is set in relation to restriction of human resources and diagnostic facilities within the peripheral prenatal clinics.

Adult↗
PubMed1988

A simple local database for audit and epidemiologic studies.

The Authors, after having outlined the importance of clinical audit in order to improve the perinatal care provided and reduce management-dishomogeneity between obstetrical staff members, present a simple off-line system of computerized perinatal data collection that has proved to be the useful for audit applications and statistical epidemiological evaluations.

Epidemiologic Methods↗
PubMed1988

Objective diagnostic information and labour-delivery management homogeneity: our experience.

Since intrapartum cardiotocography was adopted as an objective diagnostic tool, we tried to evaluate if its routine use has induced more homogeneity in management between our staff members. The analysis of some simple parameters outlines how management variability between different staff members, still outweighs the supposed objectivity of the information coming from intrapartum cardiotocography.

Adolescent↗