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Biomedical subjects

G Carrault

Publications and source records attributed to G Carrault.

9 recordsLinked to original sources

Non-linear algorithms for processing biological signals.

This paper illustrates different approaches to the analysis of biological signals based on non-linear methods. The performance of such approaches, despite the greater methodological and computational complexity is, in many instances, more successful compared to linear approaches, in enhancing important parameters for both physiological studies and clinical protocols. The methods introduced employ median filters for pattern recognition, adaptive segmentation, data compression, prediction and data modelling as well as multivariate estimators in data clustering through median learning vector quantizers. Another approach described uses Wiener-Volterra kernel technique to obtain a satisfactory estimation and causality test among EEG recordings. Finally, methods for the assessment of non-linear dynamic behaviour are discussed and applied to the analysis of heart rate variability signal. In this way invariant parameters are studied which describe non-linear phenomena in the modelling of the physiological systems under investigation.

Algorithms

Linear multivariate models for physiological signal analysis: theory.

The general linear parametric multivariate modelling concept is presented. This model combines a variety of different kinds of multivariate linear models. The concept of partial spectral analysis is derived from the general model. Some emphasis is laid on the causality demands of the model, and it is shown that the classic strictly-causal structure must be abandoned in order to utilise the modelling in many practical situations. Two special sub-class models are described in detail: the multivariate autoregressive model and the multivariate dynamic adjustment model. Furthermore, time-varying modelling is considered. The modelling of the real system is presented on a general level as a system identification cycle. The application of the methods to real physiological data is presented in the companion paper.

Data Collection

Linear multivariate models for physiological signal analysis: applications.

Some applications of linear multivariate modelling methods in the analysis of physiological signals are presented. These applications illustrate the methods in the analysis of cardiovascular dynamics, which has been one of the main application fields of the multivariate modelling during the last ten years. It is demonstrated that physiologically meaningful information about the causal interactions in the cardiovascular system can be drawn from the routinely available clinical signals. Both static and dynamic conditions are considered.

Humans

An approach to intelligent ischaemia monitoring.

The paper describes an approach to intelligent ischaemia event detection based on ECG ST-T segment analysis. ST-T trends are processed by means of a Bayesian forecasting approach using the multistate Kalman filter. A complete procedure, intended for use in CCU/ICU monitoring areas, is proposed, in order to give the clinician an intelligent monitoring tool. The approach serves to describe trends and their changes in a symbolic way. A novel aspect is its ability to observe certain features of ST-T elevation/depression not detected by other means, and to reject artefacts and erroneous events. A sensitivity of 89.58% and a predictivity of 84.31% are obtained on selected records of the European ST-T database. Using a restriction on event amplitude, the predictivity is raised to 95.55%. An ischaemia sensitivity index of 1.2 was determined. The method has been shown to be a robust and practical trend analysis tool, and seems to be appropriate for numeric/symbolic transformations in next-generation intelligent monitoring systems.

Bayes Theorem

Heart signal recognition by Hidden Markov Models: the ECG case.

Wave recognition in ECG signals by Hidden Markov Models (HMMs) relies on the stationary assumption for the set of parameters used to describe ECG waves. This approach seems unnatural and consequently generates severe errors in practice. A new class of HMMs called Modified Continuous Variable Duration HMMs is proposed to account for the specific properties of the ECG signal. An application of the latter, coupled with a multiresolution front-end analysis of the ECG is presented. Results show these methods can increase the performance of ECG recognition compared to classical HMMs.

Artificial Intelligence

Surface electromyogram automatic analysis and Guillain-Barré syndrome follow up.

An automatic and quantitative framework for the analysis of surface EMG interference patterns at maximal non-controlled force is described. The main contents are focused on different ways to represent surface EMG signals and to analyse collected data set through principal component analysis. The methods are tested on control individuals and on patients with Guillain-Barré Syndrome examined at different moments after the beginning of the disease (first week, three months, and one year). The results exhibit that a high diagnostic yield can be provided and furthermore that quantification and differentiation can be expected. Surface EMG interference pattern may be hoped to be a useful tool in daily practice.

Adult

Segmentation of depth-EEG seizure signals: method based on a physiological parameter and comparative study.

The analysis of stereoelectroencephalographic (intracerebral recording) signals provides information on the electrical activity of brain structures implied in epileptic seizures. A simple nonparametric adaptive segmentation method, based on a physiologically relevant parameter, is presented and compared with three methods reported in the literature. The comparative frame allows us to objectively test methods for their performances on the same basis. Results show that the proposed method is robust with respect to the types of change studied and easier to conduct, even if it is less accurate about the estimation of instants of change than another method presented in this study. Signals are segmented throughout the duration of seizures without parameter readjustment and generate instants of change in accordance with those interactively delimited by the clinician.

Algorithms